PMID int64 275k 40M | DateCompleted stringdate 1965-11-14 00:00:00 2025-02-28 00:00:00 ⌀ | DateRevised stringdate 2000-12-18 00:00:00 2025-02-28 00:00:00 | ISSN stringlengths 9 9 ⌀ | JournalTitle stringlengths 2 239 | ArticleTitle stringlengths 1 1.99k ⌀ | Authors stringlengths 3 61.6k ⌀ | Language stringclasses 47
values | Grants stringlengths 11 10.6k ⌀ | PublicationTypes stringlengths 4 259 | Chemicals stringlengths 3 1.33k ⌀ | CitationSubset stringclasses 2
values | ArticleIds stringlengths 6 44.3k | Abstract stringlengths 1 16.7k ⌀ | MeshTerms stringlengths 3 1.18k ⌀ | Keywords stringlengths 1 17.2k ⌀ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
22,704,930 | 2012-10-30 | 2017-11-16 | 1879-2448 | Water research | Transport of two naphthoic acids and salicylic acid in soil: experimental study and empirical modeling. | Hanna K, Lassabatere L, Bechet B | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Carboxylic Acids, Naphthalenes, Naphthols, Soil, Soil Pollutants, 1-naphthoic acid, Salicylic Acid, 1-hydroxy-2-naphthoic acid | IM | 22704930, S0043-1354(12)00292-8, 10.1016/j.watres.2012.04.037 | In contrast to the parent compounds, the mechanisms responsible for the transport of natural metabolites of polycyclic aromatic hydrocarbons (PAH) in contaminated soils have been scarcely investigated. In this study, the sorption of three aromatic acids (1-naphthoic acid (NA), 1-hydroxy-2-naphthoic acid (HNA) and salic... | Adsorption, Batch Cell Culture Techniques, Carboxylic Acids, Hydrogen-Ion Concentration, Models, Chemical, Motion, Naphthalenes, Naphthols, Salicylic Acid, Soil, Soil Pollutants, Temperature | null |
22,704,932 | 2012-10-22 | 2012-07-17 | 1090-2104 | Biochemical and biophysical research communications | Stimulation of Cryptococcus neoformans isolated from skin lesion of AIDS patient matures dendritic cells and promotes HIV-1 trans-infection. | Qin Yan, Li Yu-Ye, Jiang Ai-Ping, Jiang Jin-Feng, Wang Jian-Hua | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704932, S0006-291X(12)01093-5, 10.1016/j.bbrc.2012.06.020 | Dendritic cells (DCs) play a pivotal role in host defense against invaded pathogens including fungi, while DCs are targeted by fungi for deleterious regulation of the host immune response. A few studies have reported fungal modulation of DC function in these immunocompromised AIDS patients. Cryptococcus neoformans (C. ... | AIDS-Related Opportunistic Infections, Bacterial Translocation, Cryptococcosis, Cryptococcus neoformans, Dendritic Cells, HEK293 Cells, HIV-1, Humans, Immunocompromised Host, Lymphocyte Activation, Skin, T-Lymphocytes | null |
22,704,931 | 2012-10-22 | 2022-12-07 | 1090-2104 | Biochemical and biophysical research communications | Plasma amyloid-β oligomers level is a biomarker for Alzheimer's disease diagnosis. | Zhou L, Chan K H, Chu L W, Kwan J S C, Song Y Q, Chen L H, Ho P W L, Cheng O Y, Ho J W M, Lam K S L | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Amyloid beta-Peptides, Biomarkers, Peptide Fragments, amyloid beta-protein (1-40), amyloid beta-protein (1-42) | IM | 22704931, S0006-291X(12)01090-X, 10.1016/j.bbrc.2012.06.017 | Amyloid beta (Aβ), especially Aβ oligomers, is important in Alzheimer's disease (AD) pathogenesis. We studied plasma Aβ(40), Aβ(42), and Aβ oligomers levels in 44 AD patients and 22 non-demented controls. Cognitive functions were assessed by Chinese version of mini-mental state examination (MMSE), Abbreviated Metal Tes... | Aged, Aged, 80 and over, Alzheimer Disease, Amyloid beta-Peptides, Asian People, Biomarkers, China, Enzyme-Linked Immunosorbent Assay, Female, Humans, Male, Middle Aged, Peptide Fragments | null |
22,704,934 | 2012-09-20 | 2012-07-09 | 1090-2104 | Biochemical and biophysical research communications | Enhancer of rudimentary homolog (ERH) plays an essential role in the progression of mitosis by promoting mitotic chromosome alignment. | Fujimura Akiko, Kishimoto Hiroyuki, Yanagisawa Junn, Kimura Keiji | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Cell Cycle Proteins, Chromosomal Proteins, Non-Histone, ERH protein, human, Transcription Factors, centromere protein E | IM | 22704934, S0006-291X(12)01091-1, 10.1016/j.bbrc.2012.06.018 | The enhancer of rudimentary homolog (ERH) is a small eukaryotic protein that is highly conserved in animals, plants, and protists but not in fungi. ERH has several binding proteins and has been associated with various cellular processes, such as pyrimidine metabolism, cell cycle progression, and transcription control; ... | Cell Cycle Proteins, Chromosomal Proteins, Non-Histone, Chromosomes, Human, HeLa Cells, Humans, Kinetochores, Metaphase, Mitosis, Transcription Factors | null |
22,704,933 | 2012-10-22 | 2025-01-03 | 1090-2104 | Biochemical and biophysical research communications | Phosphorylation of the transcriptional regulator MYB44 by mitogen activated protein kinase regulates Arabidopsis seed germination. | Nguyen Xuan Canh, Hoang My Hanh Thi, Kim Ho Soo, Lee Kyunghee, Liu Xiao-Min, Kim Sun Ho, Bahk Sunghwa, Park Hyeong Cheol, Chung Woo Sik | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Arabidopsis Proteins, At5g67300 protein, Arabidopsis, Transcription Factors, AtMPK3 protein, Arabidopsis, MPK6 protein, Arabidopsis, Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinase Kinases | IM | 22704933, S0006-291X(12)01092-3, 10.1016/j.bbrc.2012.06.019 | The phytohormones abscisic acid (ABA) and gibberellic acid (GA) have antagonistic roles in the control of seed germination and seedling development. We report here that the transcriptional regulator MYB44 has a role in the control of seed germination in Arabidopsis thaliana. High levels of the MYB44 transcript are foun... | Arabidopsis, Arabidopsis Proteins, Gene Expression Regulation, Plant, Germination, Mitogen-Activated Protein Kinase Kinases, Mitogen-Activated Protein Kinases, Phosphorylation, Seeds, Transcription Factors | null |
22,704,936 | 2012-09-20 | 2012-07-09 | 1090-2104 | Biochemical and biophysical research communications | Novel DNA damage checkpoint in mitosis: Mitotic DNA damage induces re-replication without cell division in various cancer cells. | Hyun Sun-Yi, Rosen Eliot M, Jang Young-Joo | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704936, S0006-291X(12)01111-4, 10.1016/j.bbrc.2012.06.023 | DNA damage induces multiple checkpoint pathways to arrest cell cycle progression until damage is repaired. In our previous reports, when DNA damage occurred in prometaphase, cells were accumulated in 4 N-DNA G1 phase, and mitosis-specific kinases were inactivated in dependent on ATM/Chk1 after a short incubation for re... | Apoptosis, Cell Division, Cell Line, Tumor, DNA Damage, DNA Replication, G1 Phase Cell Cycle Checkpoints, HeLa Cells, Humans, Mitosis, Neoplasms | null |
22,704,935 | 2012-11-06 | 2012-07-23 | 1090-2104 | Biochemical and biophysical research communications | A versatile PCR-based tandem epitope tagging system for Streptomyces coelicolor genome. | Kim Ji-Nu, Yi Jeong Sang, Lee Bo-Rahm, Kim Eun-Jung, Kim Min Woo, Song Yoseb, Cho Byung-Kwan, Kim Byung-Gee | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Bacterial Proteins, Epitopes | IM | 22704935, S0006-291X(12)01110-2, 10.1016/j.bbrc.2012.06.022 | Epitope tagging approaches have been widely used for the analysis of functions, interactions and subcellular distributions of proteins. However, incorporating epitope sequence into protein loci in Streptomyces is time-consuming procedure due to the absence of the versatile tagging methods. Here, we developed a versatil... | Bacterial Proteins, Drug Resistance, Bacterial, Epitopes, Genetic Engineering, Genome, Bacterial, Plasmids, Polymerase Chain Reaction, Streptomyces coelicolor | null |
22,704,937 | 2012-11-29 | 2022-03-21 | 1878-5875 | The international journal of biochemistry & cell biology | Selective modulation of different GABAA receptor isoforms by diazepam and etomidate in hippocampal neurons. | Seymour Victoria A L, Curmi John P, Howitt Susan M, Casarotto Marco G, Laver Derek R, Tierney M Louise | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Protein Isoforms, Receptors, GABA-A, Diazepam, Etomidate | IM | 22704937, S1357-2725(12)00192-6, 10.1016/j.biocel.2012.06.001 | Diazepam modulation of native γ2-containing GABA(A) (γGABA(A)) receptors increases channel conductance by facilitating protein interactions involving the γ2-subunit amphipathic (MA) region, which is found in the cytoplasmic loop between transmembrane domains 3 and 4 (Everitt et al., 2009). However, many drugs, predicte... | Amino Acid Sequence, Animals, Diazepam, Electric Conductivity, Etomidate, Female, Hippocampus, Hydrophobic and Hydrophilic Interactions, Male, Models, Molecular, Molecular Sequence Data, Neurons, Permeability, Protein Isoforms, Protein Structure, Secondary, Rats, Rats, Wistar, Receptors, GABA-A | null |
22,704,941 | 2013-09-04 | 2021-10-21 | 1578-1275 | Atencion primaria | [Working with our smoker patients in primary care. Analysis of cost-effectiveness]. | Castañal-Canto Xulio, Martín-Miguel María Victoria, Hervés-Beloso Cristina, Pérez-Cachafeiro Santiago, Espinosa-Arévalo María Mercedes, Delgado-Martín José Luis | spa | null | English Abstract, Journal Article | null | IM | 22704941, S0212-6567(12)00162-X, 10.1016/j.aprim.2012.02.013, PMC7025639, 15213107, 12106550, 12113733, 12495172, 19674514, 14985603, 2740549, 9707823, 12837716, 11578560, 20619509, 15087348, 9470183, 17419933 | The aim of this work is to realize an economic evaluation of the smoking interventions in Primary Care (PC). | Cost-Benefit Analysis, Cross-Sectional Studies, Decision Trees, Direct Service Costs, Family Practice, Humans, Primary Health Care, Sensitivity and Specificity, Smoking, Smoking Cessation, Time Factors | null |
22,704,942 | 2012-12-12 | 2022-03-10 | 1532-2777 | Medical hypotheses | P75 neurotrophin receptor is a regulatory factor in sudden cardiac death with myocardial infarction. | Yuan Ming-Jie, Huang He, Huang Cong-Xin | eng | null | Journal Article | Receptor, Nerve Growth Factor | IM | 22704942, S0306-9877(12)00258-7, 10.1016/j.mehy.2012.05.035 | Sudden cardiac death (SCD) is a major cause of morbidity and mortality in patients with coronary artery diseases and myocardial infarction (MI). Sympathetic stimulation and sympathetic neural remodeling are important in the generation of SCD in diseased heart. The balance of nerve growth factor (NGF) and semaphoring 3A... | Death, Sudden, Cardiac, Humans, Models, Theoretical, Myocardial Infarction, Receptor, Nerve Growth Factor | null |
22,704,943 | 2012-12-12 | 2012-08-08 | 1532-2777 | Medical hypotheses | Hygiene hypothesis: why south/north geographical differences in prevalence of asthma and sarcoidosis? | Kurata Atsushi | eng | null | Journal Article | null | IM | 22704943, S0306-9877(12)00259-9, 10.1016/j.mehy.2012.05.036 | Although asthma is multi-factorial and generally worsens during winter, prevalence of asthma tends to be higher in warm regions. By contrast, sarcoidosis, which like asthma results from immunological abnormalities that disturb the lower respiratory tracts and unlike asthma is characterized by T helper (Th) 1 response, ... | Asthma, Geography, Humans, Models, Theoretical, Prevalence, Sarcoidosis | null |
22,704,944 | 2013-03-05 | 2022-03-09 | 1476-5411 | Contact lens & anterior eye : the journal of the British Contact Lens Association | Changes in central corneal thickness values after instillation of oxybuprocaine hydrochloride 0.4%. | Ogbuehi Kelechi C, Chijuka John C, Osuagwu Uchechukwu L | eng | null | Journal Article, Randomized Controlled Trial | Anesthetics, Local, Procaine, benoxinate | IM | 22704944, S1367-0484(12)00057-4, 10.1016/j.clae.2012.05.004 | To assess the variation in central corneal thickness (CCT) following the instillation of oxybuprocaine hydrochloride (0.4%), in normal subjects. | Adult, Anesthetics, Local, Cornea, Corneal Topography, Female, Humans, Male, Microscopy, Ophthalmoscopy, Organ Size, Procaine, Reproducibility of Results, Sensitivity and Specificity, Young Adult | null |
22,704,939 | 2015-06-22 | 2015-11-19 | 2340-3284 | Revista espanola de anestesiologia y reanimacion | [Miller-Fisher variant of Guillain-Barré syndrome in the Resuscitation Unit]. | López Erausquin N, Aguilera Celorrio L | spa | null | Case Reports, Letter | Immunoglobulins, Intravenous, Influenza Vaccines | IM | 22704939, S0034-9356(12)00177-6, 10.1016/j.redar.2012.05.003 | null | Aged, Combined Modality Therapy, Comorbidity, Critical Care, Female, Humans, Immunoglobulins, Intravenous, Influenza Vaccines, Intensive Care Units, Intubation, Intratracheal, Miller Fisher Syndrome, Plasmapheresis, Respiration, Artificial | null |
22,704,938 | 2015-11-05 | 2012-08-06 | 2340-3284 | Revista espanola de anestesiologia y reanimacion | [Use of the McGrath® video laryngoscope and paediatric tube exchanger for endotrachial tube replacement in a patient with a difficult airway]. | Ramos Costoya J, Añez Simón C, Santos Marqués M L | spa | null | Case Reports, Letter | null | IM | 22704938, S0034-9356(12)00178-8, 10.1016/j.redar.2012.05.004 | null | Accidents, Traffic, Airway Management, Anthropometry, Bronchoscopy, Fiber Optic Technology, Fracture Fixation, Internal, Humans, Intubation, Intratracheal, Laryngoscopes, Male, Middle Aged, Skull Fractures, Video Recording | null |
22,704,946 | 2012-11-20 | 2022-03-16 | 1532-2653 | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia | Correlation of leukocytosis with early neurological deterioration following supratentorial intracerebral hemorrhage. | Sun Wei, Peacock Amanda, Becker Jane, Phillips-Bute Barbara, Laskowitz Daniel T, James Michael L | eng | D43 TW008303 (FIC NIH HHS, United States); D43 TW008308 (FIC NIH HHS, United States); L30 NS071908 (NINDS NIH HHS, United States); D43-TW008308-01 (FIC NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | null | IM | 22704946, S0967-5868(12)00023-9, 10.1016/j.jocn.2011.11.020, PMC3706635, NIHMS387789, 12383357, 21387381, 20692165, 15304576, 17478736, 16905751, 18830379, 8711791, 19828550, 11283388, 8058133, 21057958, 17502545, 19109539, 19910545, 12805488, 17379820, 20934153, 20948399, 19803787, 8996478, 18556582, 19505208, 3975963... | Intracerebral hemorrhage (ICH) is a devastating and common admitting diagnosis to intensive care units in the USA. Despite advances in critical care, patients with ICH often experience early neurological deterioration (END) in the first 72 hours after admission due to a variety of factors, including hematoma and cerebr... | Adult, Aged, Aged, 80 and over, Analysis of Variance, Cerebral Hemorrhage, Female, Glasgow Coma Scale, Humans, Leukocyte Count, Leukocytosis, Male, Middle Aged, Nervous System Diseases, Statistics as Topic, Tomography, X-Ray Computed | null |
22,704,945 | 2012-11-20 | 2018-12-01 | 1532-2653 | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia | Systematic review of primary intracranial glioblastoma multiforme with symptomatic spinal metastases, with two illustrative patients. | Shahideh Mehdi, Fallah Aria, Munoz David G, Loch Macdonald R | eng | null | Case Reports, Journal Article, Review, Systematic Review | null | IM | 22704945, S0967-5868(11)00654-0, 10.1016/j.jocn.2011.09.024 | Glioblastoma multiforme is a malignant tumour with a universally fatal diagnosis. We report two patients with glioblastoma with symptomatic metastasis to the spinal cord and perform a systematic review all 35 reports of symptomatic glioblastoma dissemination to the spinal leptomeninges and/or intramedullary spinal axis... | Adult, Brain Neoplasms, Female, Glioblastoma, Humans, Kaplan-Meier Estimate, Magnetic Resonance Imaging, Male, Middle Aged, Spinal Cord Neoplasms, Tomography, X-Ray Computed | null |
22,704,947 | 2013-03-07 | 2012-10-05 | 1532-2653 | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia | A comparison of the hemodynamic effects of flow diverters on wide-necked and narrow-necked cerebral aneurysms. | Wu Yong-Fa, Yang Peng-Fei, Shen Jie, Huang Qing-Hai, Zhang Xing, Qian Yi, Liu Jian-Min | eng | null | Comparative Study, Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704947, S0967-5868(12)00018-5, 10.1016/j.jocn.2011.10.015 | Flow diverters (FD), a new generation of intracranial stents with a low porosity mesh, have been applied as an alternative treatment for intracranial aneurysms. However, their efficacy varies among aneurysms of different morphology. In this study, computational fluid dynamic simulations were performed to examine the in... | Cerebrovascular Circulation, Computer Simulation, Equipment Design, Hemodynamics, Humans, Intracranial Aneurysm, Models, Anatomic, Shear Strength, Stents | null |
22,704,948 | 2012-11-20 | 2022-04-08 | 1532-2653 | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia | Surgical management of intradural extramedullary tumors located anteriorly to the spinal cord. | Joaquim Andrei Fernandes, Almeida João Paulo, Dos Santos Marcos Juliano, Ghizoni Enrico, de Oliveira Evandro, Tedeschi Helder | eng | null | Case Reports, Journal Article | null | IM | 22704948, S0967-5868(12)00037-9, 10.1016/j.jocn.2011.08.044 | Meningiomas and nerve sheath tumors are the most common lesions found in the intradural extramedullary compartment of the spine. Some of these lesions can be located anteriorly to the spinal cord, constituting a challenge for spine surgeons. We present a surgical technique that improves the surgical exposure of lesions... | Adult, Female, Humans, Laminectomy, Magnetic Resonance Imaging, Male, Meningeal Neoplasms, Meningioma, Middle Aged, Neurosurgical Procedures, Spinal Cord, Young Adult | null |
22,704,949 | 2012-10-16 | 2015-11-19 | 1095-6859 | Gynecologic oncology | Laparoscopic lymph node dissection should be performed before fertility preserving treatment of patients with cervical cancer. | Vercellino Giuseppe F, Piek Jurgen M J, Schneider Achim, Köhler Christhardt, Mangler Mandy, Speiser Dorothee, Chiantera Vito | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Paclitaxel, Cisplatin, Ifosfamide | IM | 22704949, S0090-8258(12)00406-4, 10.1016/j.ygyno.2012.05.033 | The aim of this study is to assess our results of treatment of women with stage I cervical cancer>2 cm in diameter seeking fertility preservation. Treatment consisted of Laparoscopic Pelvic and Paraaortic Lymphadenectomy (LPPLND), and when no nodal metastasis was detected, neoadjuvant chemotherapy (NACT) followed by ra... | Adenocarcinoma, Adult, Antineoplastic Combined Chemotherapy Protocols, Brachytherapy, Carcinoma, Squamous Cell, Cervix Uteri, Chemoradiotherapy, Chemotherapy, Adjuvant, Cisplatin, Female, Fertility Preservation, Follow-Up Studies, Humans, Ifosfamide, Laparoscopy, Lymph Node Excision, Lymphatic Metastasis, Neoadjuvant T... | null |
22,704,950 | 2013-02-06 | 2015-11-19 | 1095-6859 | Gynecologic oncology | Health related quality of life and symptoms after pelvic lymphadenectomy or radiotherapy vs. no adjuvant regional treatment in early-stage endometrial carcinoma: a large population-based study. | van de Poll-Franse Lonneke V, Pijnenborg Johanna M A, Boll Dorry, Vos M Caroline, van den Berg Hetty, Lybeert Marnix L M, de Winter Karin, Kruitwagen Roy F P M | eng | null | Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't | null | IM | 22704950, S0090-8258(12)00445-3, 10.1016/j.ygyno.2012.06.007 | Routine lymphadenectomy (LA) in early stage endometrial cancer does not improve survival. However, in the absence of lymph node metastasis, radiotherapy (RT) could be withheld and hence could result in less morbidity. Our aim was to evaluate health related quality of life (HRQL) in endometrial cancer survivors that rec... | Aged, Brachytherapy, Endometrial Neoplasms, Female, Humans, Lymph Node Excision, Middle Aged, Neoplasm Staging, Pelvis, Quality of Life, Radiotherapy, Adjuvant, Risk Factors, Surveys and Questionnaires | null |
22,704,951 | 2013-02-06 | 2012-09-03 | 1095-6859 | Gynecologic oncology | Impact of the new FIGO 2009 staging classification for vulvar cancer on prognosis and stage distribution. | Tabbaa Zaid M, Gonzalez Jesus, Sznurkowski Jacek J, Weaver Amy L, Mariani Andrea, Cliby William A | eng | null | Journal Article, Multicenter Study | null | IM | 22704951, S0090-8258(12)00443-X, 10.1016/j.ygyno.2012.06.005 | In 2009, FIGO modified staging of vulvar cancer--the performance of the new classification relative to the prior system has not been assessed. We sought to investigate the impact of the 2009 FIGO vulvar cancer staging system on stage distribution and prognostic ability of the 2009 sub-stage classifications in a large c... | Cohort Studies, Female, Humans, Neoplasm Staging, Prognosis, Retrospective Studies, Survival Analysis, Vulvar Neoplasms | null |
22,704,953 | 2013-04-02 | 2022-03-30 | 1532-1932 | Best practice & research. Clinical obstetrics & gynaecology | Management of male-factor infertility. | Tournaye Herman J, Cohlen Ben J | eng | null | Journal Article | null | IM | 22704953, S1521-6934(12)00091-0, 10.1016/j.bpobgyn.2012.05.005 | For many years, the management of male-factor infertility has been empirical rather than evidence-based. In current clinical practice, assisted reproductive techniques are the most successful methods of alleviating male-factor infertility. To date, it remains unclear what adjuvant actions can be taken to improve the ou... | Azoospermia, Evidence-Based Medicine, Fertilization in Vitro, Humans, Infertility, Male, Insemination, Artificial, Life Style, Male, Reproductive Techniques, Assisted, Smoking Cessation, Sperm Retrieval, Varicocele | null |
22,704,952 | 2013-03-25 | 2012-10-01 | 1873-6807 | Body image | Exploring the utility of emotional awareness and negative affect in predicting body satisfaction and body distortion. | Manjrekar Eishita, Berenbaum Howard | eng | null | Journal Article | null | IM | 22704952, S1740-1445(12)00072-1, 10.1016/j.bodyim.2012.05.005 | In a sample of 304 female college students, the present study examined how body image is associated with (a) clarity of emotion; (b) attention to emotion; and (c) negative affect. Two separate facets of body image were examined: body satisfaction and body distortion. Greater clarity of emotion was associated with great... | Adolescent, Affective Symptoms, Attention, Awareness, Body Dysmorphic Disorders, Body Image, Emotions, Feedback, Psychological, Female, Humans, Perceptual Distortion, Personal Satisfaction, Risk Factors, Students, Young Adult | null |
22,704,954 | 2013-07-30 | 2016-11-26 | 0006-3002 | Biochimica et biophysica acta | Thyroid hormone receptors: the challenge of elucidating isotype-specific functions and cell-specific response. | Flamant Frédéric, Gauthier Karine | eng | null | Journal Article, Review | Protein Isoforms, Receptors, Thyroid Hormone, Thyroid Hormones | IM | 22704954, S0304-4165(12)00170-5, 10.1016/j.bbagen.2012.06.003 | Thyroid hormone receptors TRα1, TRβ1 and TRβ2 are broadly expressed and exert a pleiotropic influence on many developmental and homeostatic processes. Extensive genetic studies in mice precisely defined their respective function. | Animals, Humans, Protein Isoforms, Receptors, Thyroid Hormone, Signal Transduction, Thyroid Hormones | null |
22,704,955 | 2013-05-24 | 2021-10-21 | 1879-1506 | Archives of oral biology | Identification and characterization of neural crest-derived cells in adult periodontal ligament of mice. | Kaku Masaru, Komatsu Yoshihiro, Mochida Yoshiyuki, Yamauchi Mitsuo, Mishina Yuji, Ko Ching-Chang | eng | R21 AR057451 (NIAMS NIH HHS, United States); Z01 ES071003 (Intramural NIH HHS, United States); K99 DE021054 (NIDCR NIH HHS, United States); R01 DE019527 (NIDCR NIH HHS, United States); K08DE018695 (NIDCR NIH HHS, United States); R01DE020843 (NIDCR NIH HHS, United States); R01 DE020843 (NIDCR NIH HHS, United States); K0... | Journal Article, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't | null | IM | 22704955, S0003-9969(12)00146-X, 10.1016/j.archoralbio.2012.04.022, PMC3537832, NIHMS387295, 19161980, 16186259, 16192680, 2387234, 17158956, 10725243, 9916792, 14581408, 10686619, 12147742, 19415111, 16888282, 6297757, 17459343, 15070746, 15246727, 12674330, 12812797, 8660858, 19576204, 15613081, 12941628, 12716973, 1... | Cells derived from the neural crest (NC) contribute to the development of several adult tissues, including tooth and periodontal tissue. Here, two transgenic lines, Wnt1-Cre/ZEG and P0-Cre/ZEG, were analysed to determine the fate and distribution of neural crest cells (NCCs) in adult mouse periodontal ligament (PDL). | Animals, Cell Differentiation, Cell Separation, Immunohistochemistry, Mice, Mice, Transgenic, Multipotent Stem Cells, Neural Crest, Periodontal Ligament | null |
22,704,957 | 2013-02-05 | 2012-09-26 | 1878-5832 | Drug discovery today | The status of the art of human malignant glioma management: the promising role of targeting tumor-initiating cells. | Florio Tullio, Barbieri Federica | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Review | null | IM | 22704957, S1359-6446(12)00194-8, 10.1016/j.drudis.2012.06.001 | Glioblastoma is the most prevalent and malignant form of brain cancer, but the current available multimodality treatments yield poor survival improvement. Thus, innovative therapeutic strategies represent the challenging topic for glioblastoma management. Multidisciplinary advances, supporting current standard of care ... | Animals, Brain Neoplasms, Glioblastoma, Humans, Neoplastic Stem Cells | null |
22,704,958 | 2012-10-15 | 2021-12-03 | 1873-2968 | Biochemical pharmacology | Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125. | Caporali Simona, Alvino Ester, Levati Lauretta, Esposito Alessia I, Ciomei Marina, Brasca Maria G, Del Bufalo Donatella, Desideri Marianna, Bonmassar Enzo, Pfeffer Ulrich, D'Atri Stefania | eng | null | Journal Article, Research Support, Non-U.S. Gov't | MAS1 protein, human, N,1,4,4-tetramethyl-8-((4-(4-methylpiperazin-1-yl)phenyl)amino)-4,5-dihydro-1H-pyrazolo(4,3-h)quinazoline-3-carboxamide, Neoplasm Proteins, Protein Kinase Inhibitors, Proto-Oncogene Mas, Pyrazoles, Quinazolines, RNA, Small Interfering, Securin, pituitary tumor-transforming protein 1, human, Cyclin-... | IM | 22704958, S0006-2952(12)00402-9, 10.1016/j.bcp.2012.06.004 | We previously demonstrated that PHA-848125, a cyclin-dependent kinase inhibitor presently under Phase II clinical investigation, impairs melanoma cell growth. In this study, gene expression profiling showed that PHA-848125 significantly modulated the expression of 128 genes, predominantly involved in cell cycle control... | Cell Division, Cell Line, Tumor, Cyclin-Dependent Kinases, Down-Regulation, Gene Regulatory Networks, Humans, Melanoma, Neoplasm Proteins, Protein Kinase Inhibitors, Proto-Oncogene Mas, Proto-Oncogenes, Pyrazoles, Quinazolines, RNA, Small Interfering, Securin | null |
22,704,956 | 2013-02-05 | 2021-10-21 | 1878-5832 | Drug discovery today | Recent progress in structure-based anti-influenza drug design. | Du Juan, Cross Timothy A, Zhou Huan-Xiang | eng | R01 AI023007 (NIAID NIH HHS, United States); R01 GM058187 (NIGMS NIH HHS, United States); AI23007 (NIAID NIH HHS, United States); GM58187 (NIGMS NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Review | Antiviral Agents, Viral Proteins | IM | 22704956, S1359-6446(12)00195-X, 10.1016/j.drudis.2012.06.002, PMC3459301, NIHMS387332, 18660801, 16208317, 19557158, 19587036, 16251290, 19469531, 18235503, 3046255, 21894258, 19428595, 8457561, 16571812, 18454157, 978183, 19461581, 11090151, 12183461, 16456087, 20452227, 21930946, 10930642, 18796704, 16189083, 208240... | Seasonal and pandemic influenza have caused high morbidity and mortality worldwide. Recent emergence of influenza A H5N1 and H1N1 strains has heightened concern, especially as a result of their drug resistance. The life cycle of influenza viruses has been well studied and nearly all the viral proteins are becoming pote... | Antiviral Agents, Drug Design, Humans, Influenza, Human, Molecular Structure, Viral Proteins | null |
22,704,959 | 2013-05-31 | 2015-11-19 | 1873-2364 | Neuromuscular disorders : NMD | Brody syndrome: a clinically heterogeneous entity distinct from Brody disease: a review of literature and a cross-sectional clinical study in 17 patients. | Voermans N C, Laan A E, Oosterhof A, van Kuppevelt T H, Drost G, Lammens M, Kamsteeg E J, Scotton C, Gualandi F, Guglielmi V, van den Heuvel L, Vattemi G, van Engelen B G | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Sarcoplasmic Reticulum Calcium-Transporting ATPases | IM | 22704959, S0960-8966(12)00116-2, 10.1016/j.nmd.2012.03.012 | Brody disease is a rare inherited myopathy due to reduced sarcoplasmic reticulum Ca(2+) ATPase (SERCA)1 activity caused by mutations in ATP2A1, which causes delayed muscle relaxation and silent cramps. So far the disease has mostly been diagnosed by measurement of SERCA1 activity. Since mutation analysis became more wi... | Adolescent, Adult, Aged, Child, Cross-Sectional Studies, DNA Mutational Analysis, Female, Humans, Male, Middle Aged, Mutation, Myotonia Congenita, Phenotype, Review Literature as Topic, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Surveys and Questionnaires, Young Adult | null |
22,704,960 | 2013-01-29 | 2022-03-18 | 1873-4138 | Meat science | Effects of two transport systems on lamb welfare and meat quality. | Miranda-de la Lama G C, Salazar-Sotelo M I, Pérez-Linares C, Figueroa-Saavedra F, Villarroel M, Sañudo C, Maria G A | eng | null | Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't | Biomarkers | IM | 22704960, S0309-1740(12)00198-2, 10.1016/j.meatsci.2012.05.026 | The aim of this study was to analyse the effect of a direct transport system (DTS) versus transport with a logistic stopover system (TLS) on lamb welfare and meat quality at two seasons. A total of 96 lambs were sampled in a 2×2×2 factorial design, testing two transport systems and two seasons (summer and winter), with... | Animal Husbandry, Animals, Animals, Inbred Strains, Biomarkers, Cold Temperature, Food Quality, Hydrogen-Ion Concentration, Male, Meat, Mechanical Phenomena, Pigmentation, Seasons, Severity of Illness Index, Sheep, Sheep Diseases, Sheep, Domestic, Spain, Stress, Physiological, Stress, Psychological, Transportation | null |
22,704,962 | 2013-02-28 | 2022-03-21 | 1095-9157 | Journal of autoimmunity | Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction. | Boissier Marie-Christophe, Semerano Luca, Challal Salima, Saidenberg-Kermanac'h Nathalie, Falgarone Géraldine | eng | null | Journal Article, Review | Antirheumatic Agents, Autoantibodies, Cytokines, Rheumatoid Factor | IM | 22704962, S0896-8411(12)00088-1, 10.1016/j.jaut.2012.05.021 | Rheumatoid arthritis is an autoimmune disease characterized by the production of two known antibodies - rheumatoid factor and anti-citrullinated peptide antibody (ACPA) - against common autoantigens that are widely expressed within and outside the joints. The interactions between genes and environment are crucial in al... | Antirheumatic Agents, Arthritis, Rheumatoid, Autoantibodies, Autoimmunity, B-Lymphocytes, Cytokines, Humans, Joints, Lymphocyte Activation, Osteoclasts, Rheumatoid Factor, Synovitis, Th1 Cells, Th17 Cells | null |
22,704,961 | 2013-02-28 | 2024-03-22 | 1095-9157 | Journal of autoimmunity | T cells, murine chronic graft-versus-host disease and autoimmunity. | Eisenberg Robert A, Via Charles S | eng | R01 AI063626 (NIAID NIH HHS, United States); R01 AR034156 (NIAMS NIH HHS, United States) | Journal Article, Review | Autoantibodies, Histocompatibility Antigens Class II | IM | 22704961, S0896-8411(12)00084-4, 10.1016/j.jaut.2012.05.017, PMC3578438, NIHMS387781, 11544103, 21115734, 12857969, 2957440, 2968502, 6411402, 22525889, 15944260, 8473754, 9510164, 14634088, 10995792, 2148286, 9916752, 7704000, 12515811, 18219309, 2033370, 18725326, 11937575, 15240678, 10352243, 17079865, 6218218, 1969... | The chronic graft-versus-host disease (cGVHD) in mice is characterized by the production of autoantibodies and immunopathology characteristic of systemic lupus erythematosus (lupus). The basic pathogenesis involves the cognate recognition of foreign MHC class II of host B cells by alloreactive CD4 T cells from the dono... | Animals, Autoantibodies, Autoimmunity, B-Lymphocytes, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cell Communication, Disease Models, Animal, Female, Graft vs Host Disease, Histocompatibility Antigens Class II, Lupus Erythematosus, Systemic, Mice, Sex Factors, Tissue Donors | null |
22,704,963 | 2012-10-25 | 2014-11-20 | 1943-7811 | The Journal of molecular diagnostics : JMD | Intratumoral heterogeneity of microRNA expression in breast cancer. | Raychaudhuri Mithu, Schuster Tibor, Buchner Theresa, Malinowsky Katharina, Bronger Holger, Schwarz-Boeger Ulrike, Höfler Heinz, Avril Stefanie | eng | null | Journal Article, Research Support, Non-U.S. Gov't | MicroRNAs | IM | 22704963, S1525-1578(12)00098-0, 10.1016/j.jmoldx.2012.01.016 | Profiling studies have identified specific microRNA (miRNA) signatures in malignant tumors including breast cancer. Our aim was to assess intratumoral heterogeneity in miRNA expression levels within primary breast cancers and between axillary lymph node metastases from the same patient. Specimens of 16 primary breast c... | Breast Neoplasms, Female, Humans, Immunohistochemistry, In Vitro Techniques, MicroRNAs, Reverse Transcriptase Polymerase Chain Reaction | null |
22,704,964 | 2013-05-15 | 2012-11-29 | 1872-7646 | Human movement science | Multiple representations and mechanisms for visuomotor adaptation in young children. | Tahej Pierre-Karim, Ferrel-Chapus Carole, Olivier Isabelle, Ginhac Dominique, Rolland Jean-Pierre | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704964, S0167-9457(12)00053-X, 10.1016/j.humov.2012.02.016 | In this study, we utilized transformed spatial mappings to perturb visuomotor integration in 5-yr-old children and adults. The participants were asked to perform pointing movements under five different conditions of visuomotor rotation (from 0° to 180°), which were designed to reveal explicit vs. implicit representatio... | Adaptation, Psychological, Child, Preschool, Depth Perception, Discrimination Learning, Female, Humans, Male, Orientation, Perceptual Distortion, Problem Solving, Proprioception, Psychomotor Performance, User-Computer Interface, Young Adult | null |
22,704,965 | 2012-11-20 | 2021-12-03 | 1873-7544 | Neuroscience | GDNF induces mechanical hyperalgesia in muscle by reducing I(BK) in isolectin B4-positive nociceptors. | Hendrich J, Alvarez P, Chen X, Levine J D | eng | P01 NS053709 (NINDS NIH HHS, United States); R01 AR054635 (NIAMS NIH HHS, United States); R01 AR063312 (NIAMS NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural | Glial Cell Line-Derived Neurotrophic Factor, Glycoproteins, Lectins, Potassium Channels, Calcium-Activated, Vcan protein, rat, Versicans | IM | 22704965, S0306-4522(12)00611-2, 10.1016/j.neuroscience.2012.06.011, PMC3404506, NIHMS393321, 20237269, 2445972, 12876402, 10562340, 14643767, 17303637, 18616564, 9870346, 15525272, 19820205, 12570985, 10893418, 11593232, 11021795, 20180019, 16157274, 20105244, 19679180, 22094329, 9526023, 17523149, 20800357, 8264961, ... | We have assessed the mechanism underlying glial cell-derived neurotrophic factor (GDNF)-induced mechanical hyperalgesia in the gastrocnemius muscle, using patch clamp electrophysiology, in vivo electrophysiology and behavioral studies. Cultured isolectin B4-positive (IB4+) dorsal root ganglion neurons that innervated t... | Action Potentials, Animals, Ganglia, Spinal, Glial Cell Line-Derived Neurotrophic Factor, Glycoproteins, Hyperalgesia, Lectins, Male, Muscle, Skeletal, Nociceptors, Patch-Clamp Techniques, Potassium Channels, Calcium-Activated, Rats, Rats, Sprague-Dawley, Versicans | null |
22,704,966 | 2012-12-14 | 2021-10-21 | 1873-7544 | Neuroscience | Valproic acid increases white matter repair and neurogenesis after stroke. | Liu X S, Chopp M, Kassis H, Jia L F, Hozeska-Solgot A, Zhang R L, Chen C, Cui Y S, Zhang Z G | eng | P01 NS023393 (NINDS NIH HHS, United States); R01 AG037506 (NIA NIH HHS, United States); R01 NS075156 (NINDS NIH HHS, United States); P01 NS23393 (NINDS NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | Histone Deacetylase Inhibitors, Valproic Acid | IM | 22704966, S0306-4522(12)00612-4, 10.1016/j.neuroscience.2012.06.012, PMC3412884, NIHMS386639, 16775151, 11447328, 8784142, 6539617, 14556938, 11460777, 12728267, 8370349, 16946032, 15897262, 9600215, 21521169, 17855562, 9070757, 17371805, 19384336, 12451133, 15215303, 11274346, 12580341, 15935060, 19549282, 12411660, 1... | Acute treatment of stroke with histone deacetylase (HDAC) inhibitors has been shown to reduce ischemic cell damage; however, it is unclear whether delayed treatment with HDAC inhibitors will contribute to the brain repair and plasticity. In the present study, we investigated the effects of delayed treatment of stroke w... | Animals, Brain, Histone Deacetylase Inhibitors, Immunohistochemistry, In Situ Nick-End Labeling, Male, Nerve Fibers, Myelinated, Neurogenesis, Rats, Recovery of Function, Stroke, Valproic Acid | null |
22,704,967 | 2012-12-14 | 2024-11-05 | 1873-7544 | Neuroscience | Increased inflammation and brain injury after transient focal cerebral ischemia in activating transcription factor 3 knockout mice. | Wang L, Deng S, Lu Y, Zhang Y, Yang L, Guan Y, Jiang H, Li H | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Activating Transcription Factor 3, Atf3 protein, mouse | IM | 22704967, S0306-4522(12)00610-0, 10.1016/j.neuroscience.2012.06.010 | Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that has been shown to repress inflammatory gene expression in multiple cell types and diseases. This study was conducted to investigate the role of ATF3 in the pathological processes of cerebral ischemia and its influence on post-ischemi... | Activating Transcription Factor 3, Animals, Blotting, Western, Fluorescent Antibody Technique, In Situ Nick-End Labeling, Inflammation, Ischemic Attack, Transient, Mice, Mice, Knockout, Real-Time Polymerase Chain Reaction | null |
22,704,968 | 2012-09-13 | 2012-07-09 | 1873-3468 | FEBS letters | Synthetic biology - the state of play. | Kitney Richard, Freemont Paul | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Review | null | IM | 22704968, S0014-5793(12)00465-6, 10.1016/j.febslet.2012.06.002 | Just over two years ago there was an article in Nature entitled "Five Hard Truths for Synthetic Biology". Since then, the field has moved on considerably. A number of economic commentators have shown that synthetic biology very significant industrial potential. This paper addresses key issues in relation to the state o... | Computer-Aided Design, Industry, Reference Standards, Synthetic Biology, Technology | null |
22,704,970 | 2013-01-04 | 2018-12-01 | 1877-783X | Cancer epidemiology | The racial disparity in breast cancer mortality in the 25 largest cities in the United States. | Freund Karen M | eng | null | Letter, Comment | null | IM | 22704970, S1877-7821(12)00068-9, 10.1016/j.canep.2012.05.007 | null | Breast Neoplasms, Female, Health Status Disparities, Humans | null |
22,704,969 | 2013-06-04 | 2012-12-24 | 1873-5800 | The Knee | Intra-articular injections of hyaluronic acid induce positive clinical effects in knees of patients affected by haemophilic arthropathy. | Carulli Christian, Matassi Fabrizio, Civinini Roberto, Morfini Massimo, Tani Massimiliano, Innocenti Massimo | eng | null | Comparative Study, Journal Article | Viscosupplements, Hyaluronic Acid | IM | 22704969, S0968-0160(12)00108-1, 10.1016/j.knee.2012.05.006 | Haemophilic arthropathy is the most common clinical manifestation of haemophilia, secondary to recurrent haemarthrosis and chronic synovitis, and the knee represents the main target joint. Modern bleeding prevention has significatively limited the incidence of severe arthropathy, and primary approach is usually conserv... | Adult, Aged, Female, Follow-Up Studies, Hemarthrosis, Hemophilia A, Humans, Hyaluronic Acid, Injections, Intra-Articular, Knee Joint, Male, Middle Aged, Prospective Studies, Range of Motion, Articular, Time Factors, Treatment Outcome, Viscosupplements, Young Adult | null |
22,704,972 | 2012-12-14 | 2017-11-16 | 1879-1298 | Chemosphere | Organ-wise accumulation of fluoride in Prosopis juliflora and its potential for phytoremediation of fluoride contaminated soil. | Saini Poonam, Khan Suphiya, Baunthiyal Mamta, Sharma Vinay | eng | null | Journal Article | Soil, Soil Pollutants, Fluorides | IM | 22704972, S0045-6535(12)00655-8, 10.1016/j.chemosphere.2012.05.034 | Fluoride (F) contamination is a global environmental problem, as there is no cure of fluorosis available yet. Prosopis juliflora is a leguminous perennial, phreatophyte tree, widely distributed in arid and semi-arid regions of world. It extensively grows in F endemic areas of Rajasthan (India) and has been known as a "... | Biodegradation, Environmental, Biological Transport, Fluorides, Organ Specificity, Prosopis, Soil, Soil Pollutants | null |
22,704,971 | 2013-01-04 | 2022-03-30 | 1877-783X | Cancer epidemiology | The role of hospital-based cancer registries in low and middle income countries-The Nigerian Case Study. | Jedy-Agba Elima E, Curado Maria-Paula, Oga Emmanuel, Samaila Modupeola O, Ezeome Emmanuel R, Obiorah Christopher, Erinomo Olagoke O, Ekanem Ima-Obong A, Uka Cornelius, Mayun Ahmed, Afolayan Enoch A, Abiodun Popoola, Olasode Babatunde J, Omonisi Abidemi, Otu Theresa, Osinubi Patience, Dakum Patrick, Blattner William, Ad... | eng | 5D43TW001041-13 (FIC NIH HHS, United States); D43 CA153792 (NCI NIH HHS, United States); D43 TW001041 (FIC NIH HHS, United States); D43CA153792-01 (NCI NIH HHS, United States); U54 HG006947 (NHGRI NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural | null | IM | 22704971, S1877-7821(12)00071-9, 10.1016/j.canep.2012.05.010, PMC3438360, NIHMS387668, 20231304, 21675400, 16916463, 19339719, 22098217, 21172092, 19256757, 21095532, 21351269, 20211030, 10735343, 21610859, 19535980, 10585584, 20482860, 20331326, 22075441, 21463833, 18672214, 11588851, 20485489, 21796634, 19123741, 220... | The incidence of cancer continues to rise all over the world and current projections show that there will be 1.27 million new cases and almost 1 million deaths by 2030. In view of the rising incidence of cancer in sub-Saharan Africa, urgent steps are needed to guide appropriate policy, health sector investment and reso... | Academic Medical Centers, Female, Humans, Incidence, Longitudinal Studies, Male, Neoplasms, Nigeria, Registries, Socioeconomic Factors | null |
22,704,974 | 2013-02-26 | 2013-11-21 | 1879-1298 | Chemosphere | Fate of citalopram during water treatment with O3, ClO2, UV and Fenton oxidation. | Hörsing Maritha, Kosjek Tina, Andersen Henrik R, Heath Ester, Ledin Anna | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Chlorine Compounds, Fenton's reagent, Oxides, Water Pollutants, Chemical, Water, Citalopram, Ozone, chlorine dioxide, Hydrogen Peroxide, Iron | IM | 22704974, S0045-6535(12)00635-2, 10.1016/j.chemosphere.2012.05.024 | In the present study we investigate the fate of citalopram (CIT) at neutral pH using advanced water treatment technologies that include O(3), ClO(2) oxidation, UV irradiation and Fenton oxidation. The ozonation resulted in 80% reduction after 30 min treatment. Oxidation with ClO(2) removed>90% CIT at a dosage of 0.1 mg... | Chlorine Compounds, Citalopram, Humans, Hydrogen Peroxide, Hydrogen-Ion Concentration, Iron, Oxidation-Reduction, Oxides, Ozone, Ultraviolet Rays, Waste Disposal, Fluid, Water, Water Pollutants, Chemical | null |
22,704,973 | 2013-02-26 | 2013-11-21 | 1879-1298 | Chemosphere | Ozonation of azo dye Acid Red 14 in a microporous tube-in-tube microchannel reactor: decolorization and mechanism. | Gao Meiping, Zeng Zequan, Sun Baochang, Zou Haikui, Chen Jianfeng, Shao Lei | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Acid red 14, Azo Compounds, Coloring Agents, Environmental Pollutants, Industrial Waste, Ozone | IM | 22704973, S0045-6535(12)00719-9, 10.1016/j.chemosphere.2012.05.083 | The ozonation of synthetic wastewater containing azo dye Acid Red 14 (AR 14) was investigated in a high-throughput microporous tube-in-tube microchannel reactor. The effects of design and operating parameters such as micropore size, annular channel width, liquid volumetric flow rate, ozone-containing gas volumetric flo... | Azo Compounds, Color, Coloring Agents, Environmental Pollutants, Hydrogen-Ion Concentration, Industrial Waste, Kinetics, Microtechnology, Ozone, Porosity | null |
22,704,975 | 2012-11-28 | 2019-12-10 | 1879-1298 | Chemosphere | Assessing bioaccumulation of polybrominated diphenyl ethers for aquatic species by QSAR modeling. | Mansouri Kamel, Consonni Viviana, Durjava Mojca Kos, Kolar Boris, Öberg Tomas, Todeschini Roberto | eng | null | Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't | Environmental Pollutants, Flame Retardants, Halogenated Diphenyl Ethers | IM | 22704975, S0045-6535(12)00702-3, 10.1016/j.chemosphere.2012.05.081 | Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in textiles, foams and plastics. Highly bioaccumulative with toxic effects including developmental neurotoxicity estrogen and thyroid hormones disruption, they are considered as persistent organic pollutants (POPs) and have been found in human tissues,... | Animals, Aquatic Organisms, Environmental Exposure, Environmental Monitoring, Environmental Pollutants, Flame Retardants, Halogenated Diphenyl Ethers, Invertebrates, Models, Biological, Quantitative Structure-Activity Relationship, Vertebrates | null |
22,704,976 | 2012-10-23 | 2016-11-25 | 1879-1298 | Chemosphere | A pilot study for determining the optimal operation condition for simultaneously controlling the emissions of PCDD/Fs and PAHs from the iron ore sintering process. | Chen Yu-Cheng, Tsai Perng-Jy, Mou Jin-Luh, Kuo Yu-Chieh, Wang Shih-Min, Young Li-Hao, Wang Ya-Fen | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Air Pollutants, Industrial Waste, Polychlorinated Dibenzodioxins, Polycyclic Aromatic Hydrocarbons, Iron | IM | 22704976, S0045-6535(12)00652-2, 10.1016/j.chemosphere.2012.05.031 | In this study, the cost-benefit analysis technique was developed and incorporated into the Taguchi experimental design to determine the optimal operation combination for the purpose of providing a technique solution for controlling both emissions of PCDD/Fs and PAHs, and increasing both the sinter productivity (SP) and... | Air Pollutants, Cost-Benefit Analysis, Environmental Monitoring, Industrial Waste, Iron, Polychlorinated Dibenzodioxins, Polycyclic Aromatic Hydrocarbons | null |
22,704,977 | 2012-11-20 | 2019-12-10 | 1873-5177 | Pharmacology, biochemistry, and behavior | The investigation of neonatal MK-801 administration and physical environmental enrichment on emotional and cognitive functions in adult Balb/c mice. | Akillioglu Kubra, Babar Melik Emine, Melik Enver, Kocahan Sayad | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Neuroprotective Agents, Dizocilpine Maleate | IM | 22704977, S0091-3057(12)00154-2, 10.1016/j.pbb.2012.06.006 | N-methyl-D-aspartate (NMDA) receptors play an important role in brain maturation and developmental processes. It is known that growing up in an enriched environment has effects on emotional and cognitive performance. In our study, we evaluated the effects of physically enriched environment on the emotional and cognitiv... | Animals, Animals, Newborn, Anxiety, Body Weight, Brain, Cognition, Critical Period, Psychological, Dizocilpine Maleate, Emotions, Environment, Exploratory Behavior, Growth, Learning, Male, Maze Learning, Memory, Mice, Mice, Inbred BALB C, Motor Activity, Neuroprotective Agents, Swimming | null |
22,704,978 | 2013-01-29 | 2021-10-21 | 1096-7206 | Molecular genetics and metabolism | Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis. | Hu Jie, Lu Jui-Yun, Wong Andrew M S, Hynan Linda S, Birnbaum Shari G, Yilmaz Denis S, Streit Barbara M, Lenartowicz Ewelina M, Thompson Thomas C M, Cooper Jonathan D, Hofmann Sandra L | eng | R01 NS036867 (NINDS NIH HHS, United States); R37 NS036867 (NINDS NIH HHS, United States); NS036867 (NINDS NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | Recombinant Proteins, Thiolester Hydrolases, palmitoyl-protein thioesterase | IM | 22704978, S1096-7192(12)00198-9, 10.1016/j.ymgme.2012.05.009, PMC3444630, NIHMS379947, 7757942, 18341399, 20494602, 22310926, 22368049, 22331300, 8816748, 21946346, 4763201, 4121459, 19640925, 15965709, 15649713, 21749451, 21482164, 9870693, 9664077, 17261688, 7315333, 11589001, 16881055, 18443601, 11506414, 21990111, ... | PPT1-related neuronal ceroid lipofuscinosis (NCL) is a lysosomal storage disorder caused by deficiency in a soluble lysosomal enzyme, palmitoyl-protein thioesterase-1 (PPT1). Enzyme replacement therapy (ERT) has not been previously examined in a preclinical animal model. Homozygous PPT1 knockout mice reproduce the know... | Animals, Brain, Disease Models, Animal, Enzyme Replacement Therapy, Female, Humans, Lysosomes, Male, Mice, Mice, Knockout, Motor Activity, Neuronal Ceroid-Lipofuscinoses, Recombinant Proteins, Rotarod Performance Test, Thiolester Hydrolases, Viscera | null |
22,704,979 | 2012-12-26 | 2021-10-21 | 1567-7257 | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases | The emergence and maintenance of sickle cell hotspots in the Mediterranean. | Penman Bridget S, Gupta Sunetra, Buckee Caroline O | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704979, S1567-1348(12)00216-X, 10.1016/j.meegid.2012.06.001, PMC3438445, 22133230, 9623998, 17504739, 2473806, 5296398, 6134037, 14655880, 15942909, 6584911, 10872472, 12149194, 21427751, 3713863, 21872606, 3957693, 11545326, 5780379, 789227, 18353707, 17519411, 5808784, 18376107, 1687685, 22445352, 21907014, 1995543... | Genetic disorders of haemoglobin (haemoglobinopathies), including the thalassaemias and sickle cell anaemia, abound in historically malarious regions, due to the protection they provide against death from severe malaria. Despite the overall spatial correlation between malaria and these disorders, inter-population diffe... | Computer Simulation, Endemic Diseases, Epistasis, Genetic, Gene Flow, Gene Frequency, Greece, Italy, Mediterranean Islands, Mediterranean Region, Models, Genetic, alpha-Thalassemia, beta-Thalassemia | null |
22,704,981 | 2012-12-20 | 2022-03-18 | 1879-0402 | Current opinion in chemical biology | The XNA world: progress towards replication and evolution of synthetic genetic polymers. | Pinheiro Vitor B, Holliger Philipp | eng | MC_U105178804 (Medical Research Council, United Kingdom); U105178804 (Medical Research Council, United Kingdom) | Journal Article, Research Support, Non-U.S. Gov't, Review | Polymers, RNA, DNA | IM | 22704981, S1367-5931(12)00072-5, 10.1016/j.cbpa.2012.05.198 | Life's diversity is built on the wide range of properties and functions that can be encoded in natural biopolymers such as polypeptides and nucleic acids. However, despite their versatility, the range of chemical functionalities is limited, particularly in the case of nucleic acids. Chemical modification of nucleic aci... | DNA, DNA Replication, Evolution, Molecular, Polymers, RNA | null |
22,704,980 | 2013-12-02 | 2013-01-14 | 1578-1968 | Neurologia (Barcelona, Spain) | La Salpêtrière Hospital before Charcot: a visit described by Pedro González Velasco. | Giménez-Roldán S | eng | null | Biography, Historical Article, Journal Article | null | IM | 22704980, S0213-4853(12)00117-X, 10.1016/j.nrl.2012.03.017 | Under Charcot's leadership, La Salpêtrière was transformed into one of the world's top neurology centres. However, there is little information regarding the patient care facilities which Charcot would have encountered upon his arrival in 1862. | France, History, 19th Century, Hospitals, Psychiatric, Humans, Mental Disorders, Patient Care, Spain | null |
22,704,982 | 2012-10-26 | 2024-01-09 | 1879-355X | International journal of radiation oncology, biology, physics | International patterns of practice in the management of radiation therapy-induced nausea and vomiting. | Dennis Kristopher, Zhang Liying, Lutz Stephen, van Baardwijk Angela, van der Linden Yvette, Holt Tanya, Arnalot Palmira Foro, Lagrange Jean-Léon, Maranzano Ernesto, Liu Rico, Wong Kam-Hung, Wong Lea-Choung, Vassiliou Vassilios, Corn Benjamin W, De Angelis Carlo, Holden Lori, Wong C Shun, Chow Edward | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Antiemetics, Serotonin 5-HT3 Receptor Antagonists | IM | 22704982, S0360-3016(12)00253-2, 10.1016/j.ijrobp.2012.02.031 | To investigate international patterns of practice in the management of radiation therapy-induced nausea and vomiting (RINV). | Adult, Aged, Aged, 80 and over, Antiemetics, Disease Management, Female, Guideline Adherence, Health Care Surveys, Humans, Internationality, Male, Middle Aged, Nausea, Practice Guidelines as Topic, Practice Patterns, Physicians', Radiotherapy, Salvage Therapy, Serotonin 5-HT3 Receptor Antagonists, Vomiting | null |
22,704,983 | 2013-03-17 | 2022-03-31 | 1879-355X | International journal of radiation oncology, biology, physics | Symptomatic outcomes in relation to tumor expansion after fractionated stereotactic radiation therapy for vestibular schwannomas: single-institutional long-term experience. | Aoyama Hidefumi, Onodera Shunsuke, Takeichi Norihito, Onimaru Rikiya, Terasaka Shunsuke, Sawamura Yutaka, Shirato Hiroki | eng | null | Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704983, S0360-3016(12)00645-1, 10.1016/j.ijrobp.2012.05.003 | The effect of transient tumor expansion after conventionally fractionated stereotactic radiation therapy (SRT) on the symptomatic outcomes is not well-known. | Adolescent, Adult, Aged, Aged, 80 and over, Disease Progression, Dizziness, Dose Fractionation, Radiation, Facial Nerve Diseases, Female, Hearing, Hearing Loss, Humans, Hydrocephalus, Male, Middle Aged, Multivariate Analysis, Neoplasm Regression, Spontaneous, Neuroma, Acoustic, Radiosurgery, Salvage Therapy, Tinnitus, ... | null |
22,704,984 | 2013-03-17 | 2018-12-02 | 1879-355X | International journal of radiation oncology, biology, physics | A multi-institutional study of factors influencing the use of stereotactic radiosurgery for brain metastases. | Hodgson David C, Charpentier Anne-Marie, Cigsar Candemir, Atenafu Eshetu G, Ng Angela, Bahl Guarav, Zadeh Gelareh, San Miguel John, Menard Cynthia | eng | null | Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't | null | IM | 22704984, S0360-3016(12)00644-X, 10.1016/j.ijrobp.2012.05.002 | Stereotactic radiosurgery (SRS) for brain metastases is a relatively well-studied technology with established guidelines regarding patient selection, although its implementation is technically complex. We evaluated the extent to which local availability of SRS affected the treatment of patients with brain metastases. | Adult, Age Factors, Aged, Aged, 80 and over, Analysis of Variance, Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colorectal Neoplasms, Cranial Irradiation, Female, Humans, Kidney Neoplasms, Lung Neoplasms, Male, Melanoma, Middle Aged, Odds Ratio, Ontario, Radiosurgery, Regres... | null |
22,704,985 | 2013-02-12 | 2021-10-21 | 1879-0445 | Current biology : CB | A novel role for Bcl-2 in regulation of cellular calcium extrusion. | Ferdek Pawel E, Gerasimenko Julia V, Peng Shuang, Tepikin Alexei V, Petersen Ole H, Gerasimenko Oleg V | eng | G19/22 (Medical Research Council, United Kingdom); G0700167 (Medical Research Council, United Kingdom); G0300076 (Medical Research Council, United Kingdom); MR/J002771/1 (Medical Research Council, United Kingdom); G8801575 (Medical Research Council, United Kingdom) | Journal Article, Research Support, Non-U.S. Gov't | Inositol 1,4,5-Trisphosphate Receptors, Peptides, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-bcl-2, caloxin 3A1, Bcl2 protein, mouse, Barium, Meglumine, Vitamin K 3, Ca(2+) Mg(2+)-ATPase, Sarcoplasmic Reticulum Calcium-Transporting ATPases, Calcium | IM | 22704985, S0960-9822(12)00523-4, 10.1016/j.cub.2012.05.002, PMC3396842, 19789383, 18955969, 21964458, 12765680, 21763611, 11917155, 17924581, 9056075, 8894275, 15263017, 19765991, 10823933, 9298978, 15585581, 11248055, 15536077, 9788433, 19515844, 21818117, 20617337, 18657507, 21415859, 16388593, 11861756, 15670871, 10... | The antiapoptotic protein Bcl-2 plays important roles in Ca(2+) signaling by influencing inositol triphosphate receptors and regulating Ca(2+)-induced Ca(2+) release. Here we investigated whether Bcl-2 affects Ca(2+) extrusion in pancreatic acinar cells. We specifically blocked the Ca(2+) pumps in the endoplasmic retic... | Acinar Cells, Animals, Apoptosis, Barium, Ca(2+) Mg(2+)-ATPase, Calcium, Calcium Signaling, Cell Membrane, Cytosol, Endoplasmic Reticulum, Inositol 1,4,5-Trisphosphate Receptors, Meglumine, Mice, Mice, Inbred C57BL, Mice, Knockout, Necrosis, Pancreas, Peptides, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-bcl-2, ... | null |
22,704,986 | 2012-11-30 | 2017-11-16 | 1879-0445 | Current biology : CB | Genomic and morphological evidence converge to resolve the enigma of Strepsiptera. | Niehuis Oliver, Hartig Gerrit, Grath Sonja, Pohl Hans, Lehmann Jörg, Tafer Hakim, Donath Alexander, Krauss Veiko, Eisenhardt Carina, Hertel Jana, Petersen Malte, Mayer Christoph, Meusemann Karen, Peters Ralph S, Stadler Peter F, Beutel Rolf G, Bornberg-Bauer Erich, McKenna Duane D, Misof Bernhard | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704986, S0960-9822(12)00571-4, 10.1016/j.cub.2012.05.018 | The phylogeny of insects, one of the most spectacular radiations of life on earth, has received considerable attention. However, the evolutionary roots of one intriguing group of insects, the twisted-wing parasites (Strepsiptera), remain unclear despite centuries of study and debate. Strepsiptera exhibit exceptional la... | Animals, Biological Evolution, Genome, Insect, Genome, Mitochondrial, Insecta, Molecular Sequence Data, Phylogeny, Sequence Alignment, Sequence Analysis, DNA, Sequence Analysis, Protein | null |
22,704,987 | 2012-11-30 | 2024-06-10 | 1879-0445 | Current biology : CB | The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex. | Bianco Isaac H, Ma Leung-Hang, Schoppik David, Robson Drew N, Orger Michael B, Beck James C, Li Jennifer M, Schier Alexander F, Engert Florian, Baker Robert | eng | 1R01DA030304-01 (NIDA NIH HHS, United States); R01 EY002007 (NEI NIH HHS, United States); R01 DA030304 (NIDA NIH HHS, United States); RC2NS069407 (NINDS NIH HHS, United States); 1RC2NS069407-01 (NINDS NIH HHS, United States); RC2 NS069407 (NINDS NIH HHS, United States); R01 HL109525 (NHLBI NIH HHS, United States); R01 ... | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | null | IM | 22704987, S0960-9822(12)00579-9, 10.1016/j.cub.2012.05.026, PMC3647252, NIHMS462934, 3217526, 18264094, 1491254, 20975699, 8589427, 9914299, 14784863, 10433906, 10627598, 8821445, 15212435, 10022570, 21124455, 1619042, 16221589, 8694425, 15602884, 15558734, 21857656, 824412, 11718771, 4044944, 10934000, 19705454, 98280... | Although adult vertebrates sense changes in head position by using two classes of accelerometer, at larval stages zebrafish lack functional semicircular canals and rely exclusively on their otolithic organs to transduce vestibular information. | Animals, Eye Movements, Gravitation, Larva, Laser Therapy, Otolithic Membrane, Reflex, Vestibulo-Ocular, Saccule and Utricle, Signal Transduction, Vestibular Nuclei, Visual Perception, Zebrafish | null |
22,704,988 | 2013-02-12 | 2021-12-03 | 1879-0445 | Current biology : CB | AtABCG29 is a monolignol transporter involved in lignin biosynthesis. | Alejandro Santiago, Lee Yuree, Tohge Takayuki, Sudre Damien, Osorio Sonia, Park Jiyoung, Bovet Lucien, Lee Youngsook, Geldner Niko, Fernie Alisdair R, Martinoia Enrico | eng | null | Journal Article, Research Support, Non-U.S. Gov't | ATP-Binding Cassette Transporters, Arabidopsis Proteins, Coumaric Acids, Propionates, Lignin, p-coumaric acid | IM | 22704988, S0960-9822(12)00520-9, 10.1016/j.cub.2012.04.064 | Lignin is the defining constituent of wood and the second most abundant natural polymer on earth. Lignin is produced by the oxidative coupling of three monolignols: p-coumaryl alcohol, coniferyl alcohol, and sinapyl alcohol. Monolignols are synthesized via the phenylpropanoid pathway and eventually polymerized in the c... | ATP-Binding Cassette Transporters, Arabidopsis, Arabidopsis Proteins, Biological Transport, Coumaric Acids, Gene Expression Regulation, Plant, Lignin, Mutation, Promoter Regions, Genetic, Propionates, Protein Transport, Yeasts | null |
22,704,989 | 2012-12-26 | 2021-10-21 | 1879-0445 | Current biology : CB | Tropomyosin is essential for processive movement of a class V myosin from budding yeast. | Hodges Alex R, Krementsova Elena B, Bookwalter Carol S, Fagnant Patricia M, Sladewski Thomas E, Trybus Kathleen M | eng | R01 GM078097 (NIGMS NIH HHS, United States); GM078097 (NIGMS NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural | Actins, MYO2 protein, S cerevisiae, Protein Isoforms, Saccharomyces cerevisiae Proteins, TPM1 protein, S cerevisiae, Tropomyosin, Myosin Type V, Myosin Heavy Chains | IM | 22704989, S0960-9822(12)00588-X, 10.1016/j.cub.2012.05.035, PMC3570268, NIHMS380859, 6452159, 19478066, 10570140, 11509238, 11781333, 16378722, 20705471, 14535950, 15473852, 12791999, 15980429, 19209828, 20005107, 17640878, 11740494, 21757693, 18201966, 22084309, 6118372, 16190472, 10448864, 11381095, 7615669, 20858426... | Myosin V is an actin-based motor protein involved in intracellular cargo transport [1]. Given this physiological role, it was widely assumed that all class V myosins are processive, able to take multiple steps along actin filaments without dissociating. This notion was challenged when several class V myosins were chara... | Actins, Myosin Heavy Chains, Myosin Type V, Protein Isoforms, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Tropomyosin | null |
22,704,991 | 2012-12-26 | 2021-10-21 | 1879-0445 | Current biology : CB | Endocytosis of G protein-coupled receptors is regulated by clathrin light chain phosphorylation. | Ferreira Filipe, Foley Matthew, Cooke Alex, Cunningham Margaret, Smith Gemma, Woolley Robert, Henderson Graeme, Kelly Eamonn, Mundell Stuart, Smythe Elizabeth | eng | G0300452 (Medical Research Council, United Kingdom); G0600943 (Medical Research Council, United Kingdom); FS/11/49/28751 (British Heart Foundation, United Kingdom); PG/09/091/28074 (British Heart Foundation, United Kingdom); GR077544AIA (Wellcome Trust, United Kingdom) | Journal Article, Research Support, Non-U.S. Gov't | Clathrin Light Chains, Receptors, G-Protein-Coupled, G-Protein-Coupled Receptor Kinase 2 | IM | 22704991, S0960-9822(12)00587-8, 10.1016/j.cub.2012.05.034 | Signaling by transmembrane receptors such as G protein-coupled receptors (GPCRs) occurs at the cell surface and throughout the endocytic pathway, and signaling from the cell surface may differ in magnitude and downstream output from intracellular signaling. As a result, the rate at which signaling molecules traverse th... | Animals, Clathrin Light Chains, Clathrin-Coated Vesicles, Endocytosis, G-Protein-Coupled Receptor Kinase 2, Phosphorylation, Receptors, G-Protein-Coupled | null |
22,704,990 | 2012-12-26 | 2022-01-29 | 1879-0445 | Current biology : CB | Stochastic, adaptive sampling of information by microvilli in fly photoreceptors. | Song Zhuoyi, Postma Marten, Billings Stephen A, Coca Daniel, Hardie Roger C, Juusola Mikko | eng | BB/H013849/1 (Biotechnology and Biological Sciences Research Council, United Kingdom); E19850 (Biotechnology and Biological Sciences Research Council, United Kingdom); BB/F012071/1 (Biotechnology and Biological Sciences Research Council, United Kingdom); BB/D001900/1 (Biotechnology and Biological Sciences Research Coun... | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704990, S0960-9822(12)00634-3, 10.1016/j.cub.2012.05.047, PMC3420010, 9425553, 2892201, 11086990, 20648395, 7350542, 19180196, 7807062, 19180195, 18653755, 1486129, 11134229, 7441194, 2362184, 21957252, 8218908, 11931743, 21368135, 18478123, 1902848, 12860926, 11369048, 16249881, 16525044, 12571596, 7108487, 17923089... | In fly photoreceptors, light is focused onto a photosensitive waveguide, the rhabdomere, consisting of tens of thousands of microvilli. Each microvillus is capable of generating elementary responses, quantum bumps, in response to single photons using a stochastically operating phototransduction cascade. Whereas much is... | Adaptation, Physiological, Animals, Drosophila, Feedback, Physiological, Microvilli, Models, Biological, Photoreceptor Cells, Invertebrate, Stochastic Processes | null |
22,704,992 | 2013-02-12 | 2017-11-16 | 1879-0445 | Current biology : CB | Intraspecific directed deterrence by the mustard oil bomb in a desert plant. | Samuni-Blank Michal, Izhaki Ido, Dearing M Denise, Gerchman Yoram, Trabelcy Beny, Lotan Alon, Karasov William H, Arad Zeev | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Plant Oils, mustard oil | IM | 22704992, S0960-9822(12)00471-X, 10.1016/j.cub.2012.04.051 | Plant secondary metabolites (SMs) acting as defensive chemicals in reproductive organs such as fruit tissues play roles in both mutualistic and antagonistic interactions between plants and seed dispersers/predators. The directed-deterrence hypothesis states that SMs in ripe fruits deter seed predators but have little o... | Animals, Desert Climate, Fruit, Magnoliopsida, Mustard Plant, Plant Oils, Rodentia, Seed Dispersal, Seeds | null |
22,704,993 | 2012-11-30 | 2012-07-27 | 1879-0445 | Current biology : CB | A specialized area in limbic cortex for fast analysis of peripheral vision. | Yu Hsin-Hao, Chaplin Tristan A, Davies Amanda J, Verma Richa, Rosa Marcello G P | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704993, S0960-9822(12)00582-9, 10.1016/j.cub.2012.05.029 | In primates, prostriata is a small area located between the primary visual cortex (V1) and the hippocampal formation. Prostriata sends connections to multisensory and high-order association areas in the temporal, parietal, cingulate, orbitofrontal, and frontopolar cortices. It is characterized by a relatively simple hi... | Animals, Brain Mapping, Callitrichinae, Limbic System, Visual Pathways, Visual Perception | null |
22,704,994 | 2012-09-28 | 2022-04-08 | 1872-7786 | Chemico-biological interactions | Curcumin encapsulated in chitosan nanoparticles: a novel strategy for the treatment of arsenic toxicity. | Yadav Abhishek, Lomash Vinay, Samim M, Flora Swaran J S | eng | null | Journal Article | Biogenic Amines, Reactive Oxygen Species, Thiobarbituric Acid Reactive Substances, Glutathione, Curcumin, Arsenic | IM | 22704994, S0009-2797(12)00099-3, 10.1016/j.cbi.2012.05.011 | Water-soluble nanoparticles of curcumin were synthesized, characterized and applied as a stable detoxifying agent for arsenic poisoning. Chitosan nanoparticles of less than 50 nm in diameter containing curcumin were prepared. The particles were characterized by TEM, DLS and FT-IR. The therapeutic efficacy of the encaps... | Animals, Arsenic, Arsenic Poisoning, Biogenic Amines, Brain, Curcumin, Glutathione, Lipid Peroxidation, Liver, Male, Nanoparticles, Oxidative Stress, Rats, Rats, Wistar, Reactive Oxygen Species, Thiobarbituric Acid Reactive Substances, Tissue Distribution | null |
22,704,995 | 2012-09-28 | 2013-11-21 | 1872-7786 | Chemico-biological interactions | Anticancer effect of tert-butyl-2(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2)-pyrrolidine-1-carboxylic ester on human hepatoma HepG2 cell line. | Guo Juan, Zhang Yanjun, Zhang Jie, Liang Jun, Zeng Lihua, Guo Guozhen | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Antineoplastic Agents, BAX protein, human, Imidazoles, Pyrrolidines, Reactive Oxygen Species, bcl-2-Associated X Protein, tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester), Malondialdehyde, Glutathione | IM | 22704995, S0009-2797(12)00100-7, 10.1016/j.cbi.2012.06.001 | Tert-butyl-2(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2)-pyrrolidine-1-carboxylic ester (L-NNP) is a stable nitroxyl nitroxide radical, which have displayed cytotoxicity on human breast cancer MCF-7 and MDA-MB-231 cell lines. In the present study, we investigated the selective cytotoxicity ... | Animals, Antineoplastic Agents, Carcinoma, Hepatocellular, Cell Line, Cell Proliferation, Drug Screening Assays, Antitumor, Glutathione, Hep G2 Cells, Humans, Imidazoles, Male, Malondialdehyde, Membrane Potential, Mitochondrial, Mice, Mice, Inbred BALB C, Pyrrolidines, Reactive Oxygen Species, Xenograft Model Antitumor... | null |
22,704,997 | 2012-12-20 | 2012-07-30 | 1525-5069 | Epilepsy & behavior : E&B | Charles Dickens (1812-1870) and epilepsy. | Larner A J | eng | null | Biography, Case Reports, Historical Article, Journal Article | null | IM | 22704997, S1525-5050(12)00359-9, 10.1016/j.yebeh.2012.05.006 | To coincide with the bicentenary of the birth of Charles Dickens (1812-1870), accounts of epilepsy found in his novels and journalism have been collated and analyzed. From these, it may be inferred that Dickens was clearly aware of the difference between epilepsy and syncope and recognized different types of epilepsy a... | Epilepsy, History, 19th Century, Humans, Journalism, Literature, Modern, Male, Middle Aged | null |
22,704,996 | 2012-12-07 | 2022-04-10 | 1573-2509 | Schizophrenia research | Determinants of treatment satisfaction of schizophrenia patients: results from the ESPASS study. | Nordon Clementine, Rouillon Frederic, Barry Caroline, Gasquet Isabelle, Falissard Bruno | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Antipsychotic Agents | IM | 22704996, S0920-9964(12)00317-9, 10.1016/j.schres.2012.05.024 | Knowing the determinants of treatment satisfaction can provide better understanding of patient expectations in schizophrenia. The aim of this study was to determine which treatment-related factors were associated with treatment satisfaction, independently of patient-related or illness-related factors, in schizophrenia ... | Adolescent, Adult, Antipsychotic Agents, Cross-Sectional Studies, Female, Follow-Up Studies, France, Humans, Male, Patient Satisfaction, Psychiatric Status Rating Scales, Psychometrics, Retrospective Studies, Schizophrenia, Schizophrenic Psychology, Time Factors, Treatment Outcome, Young Adult | null |
22,705,000 | 2012-12-07 | 2012-07-30 | 1768-3254 | European journal of medicinal chemistry | Synthesis and in vitro stability of nucleoside 5'-phosphonate derivatives. | Vertuani Silvia, Baldisserotto Anna, Varani Katia, Borea Pier Andrea, De Marcos Maria Cruz Bonache, Ferraro Luca, Manfredini Stefano, Dalpiaz Alessandro | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Nucleosides, Organophosphonates, Platelet Aggregation Inhibitors | IM | 22705000, S0223-5234(12)00298-X, 10.1016/j.ejmech.2012.04.045 | Nucleoside derivatives are largely synthesized and tested to investigate their influence on platelet aggregation. It's well known that P2Y receptors play an important role in the regulation of platelet function and, as consequence, in controlling atherothrombotic events. The research of compounds that antagonize P2Y(1)... | Animals, Chemistry Techniques, Synthetic, Drug Stability, Humans, Liver, Male, Nucleosides, Organophosphonates, Platelet Aggregation Inhibitors, Rats, Rats, Wistar | null |
22,704,998 | 2012-12-20 | 2015-11-19 | 1525-5069 | Epilepsy & behavior : E&B | Behavioral and EEG effects of GABAergic manipulation of the nigro-tectal pathway in the Wistar audiogenic rat (WAR) strain II: an EEG wavelet analysis and retrograde neuronal tracer approach. | Rossetti Franco, Rodrigues Marcelo Cairrão Araújo, Marroni Simone S, Fernandes Artur, Foresti Maira Licia, Romcy-Pereira Rodrigo N, de Araújo Dráulio Barros, Garcia-Cairasco Norberto | eng | null | Journal Article, Research Support, Non-U.S. Gov't | 2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt, GABA Agents, Stilbamidines, Muscimol, gamma-Aminobutyric Acid, Bicuculline | IM | 22704998, S1525-5050(12)00341-1, 10.1016/j.yebeh.2012.04.133 | The role of the substantia nigra pars reticulata (SNPr) and superior colliculus (SC) network in rat strains susceptible to audiogenic seizures still remain underexplored in epileptology. In a previous study from our laboratory, the GABAergic drugs bicuculline (BIC) and muscimol (MUS) were microinjected into the deep la... | Acoustic Stimulation, Animals, Behavior, Animal, Bicuculline, Brain Waves, Disease Models, Animal, Electric Stimulation, Epilepsy, Reflex, GABA Agents, Male, Microinjections, Muscimol, Neural Pathways, Rats, Rats, Mutant Strains, Rats, Wistar, Stilbamidines, Substantia Nigra, Superior Colliculi, gamma-Aminobutyric Acid | null |
22,705,001 | 2012-12-07 | 2022-03-16 | 1768-3254 | European journal of medicinal chemistry | Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. | Llanos Gabriel G, Araujo Liliana M, Jiménez Ignacio A, Moujir Laila M, Bazzocchi Isabel L | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Antineoplastic Agents, Plant Extracts, Withanolides, Caspase 3, withaferin A | IM | 22705001, S0223-5234(12)00343-1, 10.1016/j.ejmech.2012.05.032 | Six new withanolides (1-6) along with eleven known ones (7-17) were isolated from the leaves of Withania aristata. Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR techniques. Semisynthesis of the minority metabolites 7 and 15 from compounds 6 and 9, respectively, as star... | Animals, Antineoplastic Agents, Apoptosis, Caspase 3, Cell Line, Tumor, Chlorocebus aethiops, Humans, Inhibitory Concentration 50, Plant Extracts, Structure-Activity Relationship, Vero Cells, Withania, Withanolides | null |
22,704,999 | 2012-12-07 | 2016-11-25 | 1768-3254 | European journal of medicinal chemistry | 3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: molecular modeling and pharmacological studies. | Colotta Vittoria, Lenzi Ombretta, Catarzi Daniela, Varano Flavia, Squarcialupi Lucia, Costagli Chiara, Galli Alessandro, Ghelardini Carla, Pugliese Anna Maria, Maraula Giovanna, Coppi Elisabetta, Pellegrini-Giampietro Domenico E, Pedata Felicita, Sabbadin Davide, Moro Stefano | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Anticonvulsants, Quinazolinones, Receptors, AMPA, Receptors, Kainic Acid, Glucose, Oxygen | IM | 22704999, S0223-5234(12)00347-9, 10.1016/j.ejmech.2012.05.036 | Based on our 3-hydroxy-7-chloroquinazoline-2,4-dione derivatives, previously reported as antagonists at ionotropic glutamate receptors, we synthesized new 3-hydroxyquinazoline-2,4-diones bearing a trifluoromethyl group at the 7-position and different groups at position 6. Glycine/NMDA, AMPA and kainate receptor binding... | Animals, Anticonvulsants, Electrophysiological Phenomena, Glucose, Hippocampus, Humans, In Vitro Techniques, Male, Mice, Molecular Docking Simulation, Oxygen, Quinazolinones, Rats, Rats, Wistar, Receptors, AMPA, Receptors, Kainic Acid, Structure-Activity Relationship, Substrate Specificity | null |
22,705,002 | 2012-11-23 | 2021-12-03 | 1873-2747 | Brain research bulletin | Anti-nociceptive effects of Tanshinone IIA (TIIA) in a rat model of complete Freund's adjuvant (CFA)-induced inflammatory pain. | Sun Shukai, Yin Yue, Yin Xin, Cao Fale, Luo Daoshu, Zhang Ting, Li Yunqing, Ni Longxing | eng | null | Journal Article | Abietanes, Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal, Cytokines, Drugs, Chinese Herbal, NF-kappa B, RNA, Messenger, TRPV Cation Channels, Trpv1 protein, rat, tanshinone, dan-shen root extract, Freund's Adjuvant | IM | 22705002, S0361-9230(12)00128-1, 10.1016/j.brainresbull.2012.06.002 | Inflammatory pain is an important clinical symptom. The levels of extracellular signal-regulated kinases (ERKs) and the levels of cytokines such as interleukin 1β (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-α) play important roles in inflammatory pain. Tanshinone IIA (TIIA) is an important compon... | Abietanes, Analgesics, Non-Narcotic, Animals, Anti-Inflammatory Agents, Non-Steroidal, Arthritis, Experimental, Cytokines, Drug Evaluation, Preclinical, Drugs, Chinese Herbal, Freund's Adjuvant, Ganglia, Spinal, Gene Expression Regulation, Hot Temperature, Hyperalgesia, Lumbosacral Region, MAP Kinase Signaling System, ... | null |
22,705,003 | 2013-02-05 | 2021-12-03 | 1532-8392 | Human pathology | Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma. | Rahman Munmun, Nakayama Kentaro, Rahman Mohammed Tanjimur, Nakayama Naomi, Ishikawa Masako, Katagiri Atsuko, Iida Kouji, Nakayama Satoru, Otsuki Yoshiro, Shih Ie-Ming, Miyazaki Kohji | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Class I Phosphatidylinositol 3-Kinases, PIK3CA protein, human, Proto-Oncogene Proteins c-akt, TOR Serine-Threonine Kinases | IM | 22705003, S0046-8177(12)00091-3, 10.1016/j.humpath.2012.03.011 | Somatic mutations of PIK3CA (phosphoinositide-3-kinase) have recently been shown playing an important role in the pathogenesis of ovarian clear cell carcinoma. In this study, the frequency of PIK3CA mutations and the relationship of PIK3CA mutations with clinicopathologic and biological variables were investigated in o... | Adenocarcinoma, Clear Cell, Adult, Aged, 80 and over, Cell Line, Tumor, Class I Phosphatidylinositol 3-Kinases, Female, Humans, Middle Aged, Mutation, Ovarian Neoplasms, Phosphatidylinositol 3-Kinases, Phosphorylation, Prognosis, Proto-Oncogene Proteins c-akt, TOR Serine-Threonine Kinases | null |
22,705,004 | 2013-02-05 | 2017-11-16 | 1532-8392 | Human pathology | Mucinous breast carcinomas lack PIK3CA and AKT1 mutations. | Kehr Elizabeth L, Jorns Julie M, Ang Daphne, Warrick Andrea, Neff Tanaya, Degnin Michelle, Lewis Rebecca, Beadling Carol, Corless Christopher L, Troxell Megan L | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Phosphatidylinositol 3-Kinases, Class I Phosphatidylinositol 3-Kinases, PIK3CA protein, human, Receptor, ErbB-2, AKT1 protein, human, Proto-Oncogene Proteins c-akt | IM | 22705004, S0046-8177(12)00092-5, 10.1016/j.humpath.2012.03.012 | Activating point mutations in the phosphatidylinositol-3-kinase catalytic subunit (PIK3CA) are among the most common molecular defects in invasive breast cancer. Point mutations in the downstream kinase AKT1 are seen in a minority of carcinomas. These mutations are found preferentially in estrogen receptor-positive and... | Adenocarcinoma, Mucinous, Adult, Aged, Aged, 80 and over, Breast Neoplasms, Carcinoma, Ductal, Breast, Class I Phosphatidylinositol 3-Kinases, DNA Mutational Analysis, Female, Humans, Middle Aged, Mutation, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptor, ErbB-2 | null |
22,705,005 | 2013-02-05 | 2015-11-19 | 1532-8392 | Human pathology | Immunohistochemical characteristics and malignant progression of hepatic cystic neoplasms in comparison with pancreatic counterparts. | Matsubara Takashi, Sato Yasunori, Sasaki Motoko, Harada Kenichi, Nomoto Kazuhiro, Tsuneyama Koichi, Nakamura Koichi, Gabata Toshifumi, Matsui Osamu, Nakanuma Yasuni | eng | null | Comparative Study, Journal Article | Biomarkers, Tumor, Keratin-7, Mucins, Amylases, Trypsin | IM | 22705005, S0046-8177(12)00087-1, 10.1016/j.humpath.2012.03.007 | The recent World Health Organization classification for tumors of the digestive system defined grossly and histologically hepatic mucinous cystic neoplasms and intraductal papillary neoplasms of the bile duct separately. In this study, the immunohistochemical features of intraductal papillary neoplasm of the bile duct ... | Amylases, Biomarkers, Tumor, Disease Progression, Female, Humans, Immunohistochemistry, Keratin-7, Liver Neoplasms, Male, Mucins, Neoplasms, Cystic, Mucinous, and Serous, Pancreatic Neoplasms, Trypsin | null |
22,705,007 | 2012-11-06 | 2022-12-07 | 1528-0012 | Gastroenterology | Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma. | Maréchal Raphaël, Bachet Jean-Baptiste, Mackey John R, Dalban Cécile, Demetter Pieter, Graham Kathryn, Couvelard Anne, Svrcek Magali, Bardier-Dupas Armelle, Hammel Pascal, Sauvanet Alain, Louvet Christophe, Paye François, Rougier Philippe, Penna Christophe, André Thierry, Dumontet Charles, Cass Carol E, Jordheim Lars P... | eng | null | Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't | Antimetabolites, Antineoplastic, Equilibrative Nucleoside Transporter 1, SLC29A1 protein, human, Tumor Suppressor Proteins, Deoxycytidine, RRM1 protein, human, Ribonucleoside Diphosphate Reductase, Deoxycytidine Kinase, Gemcitabine | IM | 22705007, S0016-5085(12)00822-0, 10.1053/j.gastro.2012.06.006 | Patients who undergo surgery for pancreatic ductal adenocarcinoma (PDAC) frequently receive adjuvant gemcitabine chemotherapy. Key determinants of gemcitabine cytotoxicity include the activities of the human equilibrative nucleoside transporter 1 (hENT1), deoxycytidine kinase (dCK), and ribonucleotide reductase subunit... | Antimetabolites, Antineoplastic, Biological Transport, Biotransformation, Carcinoma, Pancreatic Ductal, Chemotherapy, Adjuvant, Chi-Square Distribution, Deoxycytidine, Deoxycytidine Kinase, Equilibrative Nucleoside Transporter 1, Female, France, Humans, Immunohistochemistry, Kaplan-Meier Estimate, Male, Multivariate An... | null |
22,705,006 | 2012-10-01 | 2022-03-30 | 1528-0012 | Gastroenterology | A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. | Seki Ekihiro, Brenner David A, Karin Michael | eng | R01AA020172 (NIAAA NIH HHS, United States); R01 AA020172 (NIAAA NIH HHS, United States); R01GM041804 (NIGMS NIH HHS, United States); P42ES010337 (NIEHS NIH HHS, United States); P42 ES010337 (NIEHS NIH HHS, United States); R01 DK085252 (NIDDK NIH HHS, United States); R01DK085252 (NIDDK NIH HHS, United States); R01 GM041... | Journal Article, Research Support, N.I.H., Extramural, Review | Analgesics, Non-Narcotic, Biomarkers, Protein Kinase Inhibitors, Acetaminophen, JNK Mitogen-Activated Protein Kinases | IM | 22705006, S0016-5085(12)00820-7, 10.1053/j.gastro.2012.06.004, PMC3523093, NIHMS393916, 19053047, 9755232, 17983584, 15793284, 16955144, 21953113, 15316358, 18393321, 15486293, 20478530, 17133482, 11148566, 21844199, 16912279, 11713531, 19041150, 18337250, 19243309, 17050683, 18700144, 8945519, 20080763, 20303879, 2068... | c-Jun-N-terminal kinase (JNK) is a mitogen-activated protein kinase family member that is activated by diverse stimuli, including cytokines (such as tumor necrosis factor and interleukin-1), reactive oxygen species (ROS), pathogens, toxins, drugs, endoplasmic reticulum stress, free fatty acids, and metabolic changes. U... | Acetaminophen, Analgesics, Non-Narcotic, Animals, Biomarkers, Carcinoma, Hepatocellular, Cell Death, Chemical and Drug Induced Liver Injury, Fatty Liver, Humans, JNK Mitogen-Activated Protein Kinases, Liver, Liver Diseases, Liver Neoplasms, Liver Regeneration, Liver Transplantation, MAP Kinase Signaling System, Metabol... | null |
22,705,008 | 2012-12-17 | 2024-12-15 | 1528-0012 | Gastroenterology | Successful vaccination induces multifunctional memory T-cell precursors associated with early control of hepatitis C virus. | Park Su-Hyung, Shin Eui-Cheol, Capone Stefania, Caggiari Laura, De Re Valli, Nicosia Alfredo, Folgori Antonella, Rehermann Barbara | eng | ZIA DK054508-12 (Intramural NIH HHS, United States); ZIA DK054508-13 (Intramural NIH HHS, United States); Z01 DK054508-11 (Intramural NIH HHS, United States); Z01 DK054508 (Intramural NIH HHS, United States); Z01 DK054508-10 (Intramural NIH HHS, United States) | Comparative Study, Journal Article, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't | B7-H1 Antigen, DNA, Viral, Interleukin-7 Receptor alpha Subunit, Programmed Cell Death 1 Receptor, RNA, Messenger, Tumor Necrosis Factor-alpha, Viral Hepatitis Vaccines, Interferon-gamma, 2',5'-Oligoadenylate Synthetase | IM | 22705008, S0016-5085(12)00821-9, 10.1053/j.gastro.2012.06.005, PMC3458177, NIHMS389706, 17039255, 16876901, 8671665, 17485666, 17258731, 16941702, 12663785, 14625547, 14576438, 16462801, 19587449, 21604986, 10229187, 12810686, 17326154, 18981091, 21699897, 18667501, 18753204, 12021342, 14671100, 14722311, 17058243, 173... | T cells are an important component for development of a vaccine against hepatitis C virus (HCV), but little is known about the features of successful vaccine-induced T cells. | 2',5'-Oligoadenylate Synthetase, Analysis of Variance, Animals, B7-H1 Antigen, CD8-Positive T-Lymphocytes, DNA, Viral, Hepacivirus, Hepatitis C, Immunologic Memory, Interferon-gamma, Interleukin-7 Receptor alpha Subunit, Liver, Mice, Mice, Inbred C57BL, Pan troglodytes, Phenotype, Precursor Cells, T-Lymphoid, Programme... | null |
22,705,010 | 2012-12-13 | 2012-07-30 | 1873-569X | Journal of dermatological science | Tyrosinase-related protein1 in mouse melanocytes at early embryonic stage. | Kawakami Tamihiro, Soma Yoshinao | eng | null | Letter, Research Support, Non-U.S. Gov't | Membrane Glycoproteins, Microphthalmia-Associated Transcription Factor, Mitf protein, mouse, Oxidoreductases, Tyrp1 protein, mouse, Monophenol Monooxygenase | IM | 22705010, S0923-1811(12)00175-2, 10.1016/j.jdermsci.2012.05.004 | null | Animals, Female, Gene Expression Regulation, Developmental, Male, Melanocytes, Membrane Glycoproteins, Mice, Mice, Inbred C57BL, Microphthalmia-Associated Transcription Factor, Monophenol Monooxygenase, Neural Crest, Oxidoreductases, Skin | null |
22,705,009 | 2012-11-06 | 2017-07-10 | 1528-0012 | Gastroenterology | Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma. | Ma Stephanie, Bao Jessie Y J, Kwan Pak Shing, Chan Yuen Piu, Tong Carol M, Fu Li, Zhang Na, Tong Amy H Y, Qin Yan-Ru, Tsao Sai Wah, Chan Kwok Wah, Lok Si, Guan Xin-Yuan | eng | null | Journal Article, Research Support, Non-U.S. Gov't | CTNNB1 protein, human, Histones, Neoplasm Proteins, RNA, Messenger, Tumor Suppressor Proteins, beta Catenin, Protein-Tyrosine Kinases, PTK6 protein, human, GSK3B protein, human, Glycogen Synthase Kinase 3 beta, Gsk3b protein, mouse, Proto-Oncogene Proteins c-akt, Glycogen Synthase Kinase 3 | IM | 22705009, S0016-5085(12)00823-2, 10.1053/j.gastro.2012.06.007 | Esophageal squamous cell carcinoma (ESCC) is the most commonly observed histologic subtype of esophageal cancer. ESCC is believed to develop via accumulation of numerous genetic alterations, including inactivation of tumor suppressor genes and activation of oncogenes. We searched for transcripts that were altered in hu... | Acetylation, Adult, Animals, Carcinoma, Squamous Cell, Cell Line, Tumor, Cell Movement, Cell Proliferation, DNA Methylation, Epigenesis, Genetic, Esophageal Neoplasms, Extracellular Matrix, Female, G1 Phase Cell Cycle Checkpoints, Gene Expression Profiling, Gene Expression Regulation, Enzymologic, Gene Expression Regul... | null |
22,705,011 | 2013-07-22 | 2012-12-03 | 1878-1519 | Respiratory physiology & neurobiology | Postnatal maturation of breathing stability and loop gain: the role of carotid chemoreceptor development. | Edwards Bradley A, Sands Scott A, Berger Philip J | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Review | null | IM | 22705011, S1569-9048(12)00144-9, 10.1016/j.resp.2012.06.003 | Any general model of respiratory control must explain a puzzling array of breathing patterns that are observed during the course of a lifetime. Particular challenges are to understand why periodic breathing is rarely seen in the first few days after birth, reaches a peak at 2-4 weeks postnatal age, and disappears by 6 ... | Carotid Body, Humans, Infant, Newborn, Respiration, Respiratory Mechanics, Respiratory System | null |
22,705,012 | 2013-04-15 | 2013-11-21 | 1878-1519 | Respiratory physiology & neurobiology | Carbon monoxide exposure in the urban environment: an insidious foe for the heart? | Reboul C, Thireau J, Meyer G, André L, Obert P, Cazorla O, Richard S | eng | null | Journal Article, Review | Air Pollutants, Carbon Monoxide | IM | 22705012, S1569-9048(12)00151-6, 10.1016/j.resp.2012.06.010 | Since Claude Bernard first demonstrated in the 19th century that carbon monoxide (CO) poisoning occurs through hemoglobin binding, CO has proven to be more than simply a toxic gas, and to possess complex biological properties. In this review, we highlight the dual nature of CO in cardiovascular function, from endogenou... | Air Pollutants, Animals, Carbon Monoxide, Electrophysiological Phenomena, Environmental Exposure, Heart Diseases, Humans, Urban Population | null |
22,705,014 | 2013-05-29 | 2012-11-16 | 1878-1780 | Diabetes & metabolism | Type 1 diabetes: dealing with physical activity. | Franc S, Dardari D, Biedzinski M, Requeda E, Canipel L, Hochberg G, Boucherie B, Charpentier G | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Blood Glucose, Hypoglycemic Agents, Insulin | IM | 22705014, S1262-3636(12)00076-6, 10.1016/j.diabet.2012.03.009 | For patients with type 1 diabetes (T1D) using multiple insulin injections (MII), there are currently no guidelines for insulin dose adjustments in the event of physical activity (PA) and no simple algorithms that can be applied directly. Thus, the objective of this study was to assess the relevance of simple algorithms... | Adult, Algorithms, Blood Glucose, Diabetes Mellitus, Type 1, Drug Administration Schedule, Exercise, Female, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin, Male, Postprandial Period, Time Factors | null |
22,705,013 | 2013-03-17 | 2022-03-09 | 1878-1519 | Respiratory physiology & neurobiology | Recovery of inspiratory intercostal muscle activity following high cervical hemisection. | Dougherty B J, Lee K Z, Gonzalez-Rothi E J, Lane M A, Reier P J, Fuller D D | eng | 1R01-NS-054025 (NINDS NIH HHS, United States); T-32 HD043730 (NICHD NIH HHS, United States); R21 HL104294 (NHLBI NIH HHS, United States); 1F31NS063659-01A2 (NINDS NIH HHS, United States); 1R21-HL104294-01 (NHLBI NIH HHS, United States); F31 NS063659 (NINDS NIH HHS, United States); R01 NS054025 (NINDS NIH HHS, United St... | Journal Article, Research Support, N.I.H., Extramural | null | IM | 22705013, S1569-9048(12)00147-4, 10.1016/j.resp.2012.06.006, PMC4288928, NIHMS429428, 18308305, 18775573, 19150658, 19560562, 11160996, 14764434, 6707715, 10963770, 12657710, 4078753, 21106900, 15871925, 7836225, 20043908, 12486024, 12228053, 8594024, 18924146, 3598633, 3411478, 15037862, 7932235, 17974589, 15788709, 1... | Anatomical and neurophysiological evidence indicates that thoracic interneurons can serve a commissural function and activate contralateral motoneurons. Accordingly, we hypothesized that respiratory-related intercostal (IC) muscle electromyogram (EMG) activity would be only modestly impaired by a unilateral cervical sp... | Animals, Cervical Vertebrae, Inhalation, Intercostal Muscles, Male, Neuronal Plasticity, Rats, Rats, Sprague-Dawley, Recovery of Function, Respiratory Mechanics, Spinal Cord Injuries | null |
22,705,015 | 2012-12-03 | 2021-10-21 | 1879-3088 | Trends in cell biology | Multi-tasking: nuclear transcription factors with novel roles in the mitochondria. | Szczepanek Karol, Lesnefsky Edward J, Larner Andrew C | eng | R01 AI059710 (NIAID NIH HHS, United States); R01 GM101677 (NIGMS NIH HHS, United States); R21 AI088487 (NIAID NIH HHS, United States); R01 AI059710-01 (NIAID NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Review | Transcription Factors | IM | 22705015, S0962-8924(12)00084-0, 10.1016/j.tcb.2012.05.001, PMC3516366, NIHMS387756, 21715323, 18391940, 16207717, 18056423, 21036145, 21930250, 19556508, 16728594, 17460192, 12567188, 10821866, 20360684, 19411846, 18988672, 15963355, 21393861, 15867370, 21747053, 11522775, 11900485, 21980124, 12867595, 9832167, 112874... | Coordinated responses between the nucleus and mitochondria are essential for the maintenance of homeostasis. For over 15 years, pools of nuclear transcription factors (TFs), such as p53 and nuclear hormone receptors, have been observed in the mitochondria. The contribution of the mitochondrial pool of these TFs to thei... | Animals, Cell Nucleus, Cell Respiration, Gene Expression Regulation, Humans, Mitochondria, Signal Transduction, Transcription Factors | null |
22,705,017 | 2012-11-13 | 2022-03-31 | 1096-0260 | Preventive medicine | Increased risk of chronic kidney disease among users of non-prescribed Chinese herbal medicine in Taiwan. | Hsieh Chuan-Fa, Huang Song-Lih, Chen Chien-Lung, Chen Wei-Ta, Chang Huan-Cheng, Wu Ming-Ling, Yang Chen-Chang | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Drugs, Chinese Herbal | IM | 22705017, S0091-7435(12)00249-6, 10.1016/j.ypmed.2012.06.003 | Taiwan has the highest incidence of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide. Chinese herbal medicine (CHM) has been linked to CKD/ESRD in Taiwan. The specific effects and frequency of CHM on the risk of CKD are unknown. | Adult, Aged, Case-Control Studies, Chronic Disease, Comorbidity, Confounding Factors, Epidemiologic, Drugs, Chinese Herbal, Exercise, Female, Health Knowledge, Attitudes, Practice, Humans, Kidney Failure, Chronic, Life Style, Male, Middle Aged, Multivariate Analysis, Proportional Hazards Models, Renal Insufficiency, Ch... | null |
22,705,016 | 2013-02-08 | 2024-08-08 | 1096-0260 | Preventive medicine | Parent-focused change to prevent obesity in preschoolers: results from the KAN-DO study. | Østbye Truls, Krause Katrina M, Stroo Marissa, Lovelady Cheryl A, Evenson Kelly R, Peterson Bercedis L, Bastian Lori A, Swamy Geeta K, West Deborah G, Brouwer Rebecca J N, Zucker Nancy L | eng | K23 MH070418 (NIMH NIH HHS, United States); P30 ES010126 (NIEHS NIH HHS, United States); 1-K23-MH-070-01 (NIMH NIH HHS, United States); R01-DK-07549 (NIDDK NIH HHS, United States); R01 DK075439 (NIDDK NIH HHS, United States) | Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural | null | IM | 22705016, S0091-7435(12)00251-4, 10.1016/j.ypmed.2012.06.005, PMC3439558, NIHMS386646, 20633234, 16611394, 14702458, 20883981, 17572310, 19413705, 17467752, 9813653, 9724677, 15047683, 10799366, 21300177, 14640806, 15488428, 16864353, 16678304, 10719403, 14084769, 11817924, 12729175, 16895873, 18463121, 15466068, 17907... | The study presents the immediate post-intervention results of Kids and Adults Now - Defeat Obesity!, a randomized controlled trial to enhance healthy lifestyle behaviors in mother-preschooler (2-5 years old) dyads in North Carolina (2007-2011). The outcomes include change from baseline in the child's diet, physical act... | Adult, Child, Preschool, Diet, Emotions, Exercise, Female, Humans, Male, Maternal Behavior, North Carolina, Obesity, Parenting | null |
22,705,018 | 2012-12-11 | 2012-08-27 | 1872-6232 | Early human development | Altered placental development in pregnancies resulting in sudden infant death syndrome (SIDS). | Widdows Kate, O'Malley Aiveen, O'Neill Bill, Kingdom John, Gillan John, Ansari Tahera | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22705018, S0378-3782(12)00134-X, 10.1016/j.earlhumdev.2012.05.006 | Sudden infant death syndrome (SIDS) is postulated to be a developmental disorder originating during fetal life in utero. Knowledge regarding the intrauterine environment in which SIDS infants develop is, however, inadequate and how the placenta develops prior to a SIDS event has not been studied. | Adolescent, Adult, Chorionic Villi, Female, Humans, Infant, Newborn, Infant, Small for Gestational Age, Male, Placenta Diseases, Pregnancy, Sudden Infant Death, Trophoblasts | null |
22,705,019 | 2012-11-02 | 2012-07-03 | 1464-3391 | Bioorganic & medicinal chemistry | Synthesis of 6-substituted 9-methoxy-11H-indeno[1,2-c]quinoline-11-one derivatives as potential anticancer agents. | Tseng Chih-Hua, Chen Yeh-Long, Yang Chiao-Li, Cheng Chih-Mei, Han Chein-Hwa, Tzeng Cherng-Chyi | eng | null | Journal Article, Research Support, Non-U.S. Gov't | 6-(3-(dimethylamino)propylamino)-9-methoxy-11H-indeno(1,2-c)quinolin-11-one, Antineoplastic Agents, Indenes, Quinolizidines, Quinolones, Poly(ADP-ribose) Polymerases, Caspase 3, Caspase 8 | IM | 22705019, S0968-0896(12)00409-9, 10.1016/j.bmc.2012.05.035 | We have synthesized certain 6-substituted 9-methoxy-11H-indeno[1,2-c]quinolin-11-ones for antiproliferative evaluation. Results indicated that 6-alkylamine derivatives, 6-[2-(dimethylamino)ethylamino]-9-methoxy-11H-indeno[1,2-c]quinolin-11-one (5a) and its 6-[3-(dimethylamino)propylamino] derivative, 5b, were able to i... | Antineoplastic Agents, Apoptosis, Caspase 3, Caspase 8, Cell Line, Tumor, G2 Phase Cell Cycle Checkpoints, Humans, Indenes, M Phase Cell Cycle Checkpoints, Poly(ADP-ribose) Polymerases, Quinolizidines, Quinolones | null |
22,705,020 | 2012-11-02 | 2024-06-10 | 1464-3391 | Bioorganic & medicinal chemistry | Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. | Johnson Tyler A, Sohn Johann, Vaske Yvette M, White Kimberly N, Cohen Tanya L, Vervoort Helene C, Tenney Karen, Valeriote Frederick A, Bjeldanes Leonard F, Crews Phillip | eng | U01 TW008160 (FIC NIH HHS, United States); R01 CA047135 (NCI NIH HHS, United States); 1U01TW008160-01 (FIC NIH HHS, United States); R01 CA 47135 (NCI NIH HHS, United States); T34 GM007910 (NIGMS NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S. | Alkaloids, Azepines, Chemokine CCL2, Immunologic Factors, Interleukin-6, Lipopolysaccharides, NF-kappa B, Tumor Necrosis Factor-alpha, bengamide E, Nitric Oxide Synthase Type II, I-kappa B Kinase | IM | 22705020, S0968-0896(12)00417-8, 10.1016/j.bmc.2012.05.043, PMC3417756, NIHMS388161, 16879738, 11809076, 15332835, 19046569, 17072334, 11438690, 12656172, 9790549, 17622130, 18657422, 8557566, 20866076, 18060028, 20179242, 11997170, 20520915, 11671930, 7568127, 17072321, 11170681, 10048565, 21465667, 11606134, 16651429... | A nuclear factor-κB (NF-κB) luciferase assay has been employed to identify the bengamides, previously known for their anti-tumor activity, as a new class of immune modulators. A unique element of this study was that the bengamide analogs were isolated from two disparate sources, Myxococcus virescens (bacterium) and Jas... | Alkaloids, Animals, Azepines, Chemokine CCL2, Chromatography, High Pressure Liquid, HCT116 Cells, Humans, I-kappa B Kinase, Immunologic Factors, Interleukin-6, Lipopolysaccharides, Macrophages, Mass Spectrometry, Mice, Myxococcales, NF-kappa B, Nitric Oxide Synthase Type II, Phosphorylation, Porifera, Tumor Necrosis Fa... | null |
22,705,021 | 2012-11-02 | 2018-12-01 | 1464-3391 | Bioorganic & medicinal chemistry | Functional characterization of recombinant hyoscyamine 6β-hydroxylase from Atropa belladonna. | Li Jing, van Belkum Marco J, Vederas John C | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Oxygen Isotopes, Plant Proteins, Recombinant Proteins, Scopolamine, Mixed Function Oxygenases, hyoscyamine (6S)-dioxygenase | IM | 22705021, S0968-0896(12)00416-6, 10.1016/j.bmc.2012.05.042 | (-)-Hyoscyamine, the enantiomerically pure form of atropine, and its derivative scopolamine are tropane alkaloids that are extensively used in medicine. Hyoscyamine 6β-hydroxylase (H6H, EC 1.14.11.11), a monomeric α-ketoglutarate dependent dioxygenase, converts (-)-hyoscyamine to its 6,7-epoxy derivative, scopolamine, ... | Atropa belladonna, Kinetics, Mixed Function Oxygenases, Oxidation-Reduction, Oxygen Isotopes, Plant Proteins, Recombinant Proteins, Scopolamine, Stereoisomerism, Substrate Specificity | null |
22,705,022 | 2012-11-02 | 2012-11-15 | 1464-3391 | Bioorganic & medicinal chemistry | Synthesis, biological evaluation and molecular docking studies of 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N-phenylacrylamide derivatives as inhibitors of HDAC activity. | Li Xi, Liu Jia-Lin, Yang Xian-Hui, Lu Xiang, Zhao Ting-Ting, Gong Hai-Bin, Zhu Hai-Liang | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Acrylamides, Antineoplastic Agents, Histone Deacetylase Inhibitors, N-(4-bromophenyl)-3-(3-(4-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamide, N-phenylacrylamide, Pyrazoles, pyrazole, Histone Deacetylases | IM | 22705022, S0968-0896(12)00405-1, 10.1016/j.bmc.2012.05.031 | In present study, a series of 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N-phenylacrylamide derivatives (5a-8d) were designed, synthesized, and evaluated for HDAC inhibition and tumor cell antiproliferation. All of these compounds are reported for the first time, the chemical structures of these compounds were confirmed by means... | Acrylamides, Antineoplastic Agents, Binding Sites, Cell Line, Tumor, Cell Proliferation, Computer Simulation, Drug Screening Assays, Antitumor, HCT116 Cells, Histone Deacetylase Inhibitors, Histone Deacetylases, Humans, Protein Structure, Tertiary, Pyrazoles, Structure-Activity Relationship | null |
22,705,024 | 2012-12-21 | 2024-01-09 | 1879-0356 | Current opinion in plant biology | Plant pattern recognition receptor complexes at the plasma membrane. | Monaghan Jacqueline, Zipfel Cyril | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Review | Membrane Proteins, Receptors, Pattern Recognition | IM | 22705024, S1369-5266(12)00087-8, 10.1016/j.pbi.2012.05.006 | A key feature of innate immunity is the ability to recognize and respond to potential pathogens in a highly sensitive and specific manner. In plants, the activation of pattern recognition receptors (PRRs) by pathogen-associated molecular patterns (PAMPs) elicits a defense programme known as PAMP-triggered immunity (PTI... | Cell Membrane, Disease Resistance, Host-Pathogen Interactions, Membrane Proteins, Plant Diseases, Plant Immunity, Plants, Receptors, Pattern Recognition, Signal Transduction | null |
22,705,023 | 2012-11-02 | 2016-11-25 | 1464-3391 | Bioorganic & medicinal chemistry | Quencher-free molecular beacon tethering 7-hydroxycoumarin detects targets through protonation/deprotonation. | Kashida Hiromu, Yamaguchi Kyohei, Hara Yuichi, Asanuma Hiroyuki | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Amino Alcohols, Butylene Glycols, Intercalating Agents, Protons, Umbelliferones, threoninol, 7-hydroxycoumarin, DNA | IM | 22705023, S0968-0896(12)00439-7, 10.1016/j.bmc.2012.05.052 | In this study, we synthesized a simple but efficient quencher-free molecular beacon tethering 7-hydroxycoumarin on D-threoninol based on its pK(a) change. The pK(a) of 7-hydroxycoumarin in a single strand was determined as 8.8, whereas that intercalated in the duplex was over 10. This large pK(a) shift (more than 1.2) ... | Amino Alcohols, Butylene Glycols, DNA, Hydrogen-Ion Concentration, Intercalating Agents, Kinetics, Nucleic Acid Denaturation, Nucleic Acid Hybridization, Protons, Umbelliferones | null |
22,705,025 | 2013-05-20 | 2012-12-03 | 2210-741X | Clinics and research in hepatology and gastroenterology | Evaluation of preoperative predictors of development of pouchitis after ileal-pouch-anastomosis in ulcerative colitis. | Kalkan I H, Dağli Ü, Önder F O, Tunç B, Öztaş E, Ülker A, Şaşmaz N | eng | null | Journal Article | null | IM | 22705025, S2210-7401(12)00131-3, 10.1016/j.clinre.2012.04.012 | In this retrospective study, we aimed to evaluate preoperative predictive risk factors for development of pouchitis in the ulcerative colitis (UC) patients with ileal pouch-anal anastomosis (IPAA). | Adult, Anastomosis, Surgical, Colitis, Ulcerative, Colonic Pouches, Female, Humans, Ileum, Male, Pouchitis, Preoperative Period, Retrospective Studies, Risk Assessment | null |
22,705,026 | 2012-09-25 | 2016-11-25 | 1879-0038 | Gene | Molecular characterization and concerted evolution of two genes encoding RING-C2 type proteins in rice. | Jung Chang Gyo, Lim Sung Don, Hwang Sun-Goo, Jang Cheol Seong | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Carrier Proteins, Plant Proteins, Ubiquitin-Protein Ligases | IM | 22705026, S0378-1119(12)00679-8, 10.1016/j.gene.2012.05.060 | RING (Really Interesting New Gene) finger proteins are believed to play a critical role in mediating the transfer of ubiquitin to heterogeneous substrate(s). While the two canonical types, RING-H2 and RING-HC, have been well-characterized, the molecular functions of the modified types, particularly the RING-C2 types, r... | Arabidopsis, Carrier Proteins, Chromosomes, Plant, Cytoplasm, Evolution, Molecular, Genes, Plant, Oryza, Plant Proteins, Protein Structure, Tertiary, Ubiquitin-Protein Ligases | null |
22,705,027 | 2012-10-11 | 2012-07-24 | 1879-0038 | Gene | Variable intron/exon structure in the oligochaete lombricine kinase gene. | Doumen Chris | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Phosphotransferases (Nitrogenous Group Acceptor), lombricine kinase | IM | 22705027, S0378-1119(12)00700-7, 10.1016/j.gene.2012.06.007 | Lombricine kinase is an annelid enzyme that belongs to the phosphagen kinase family of which creatine kinase and arginine kinase are the typical representatives. The enzymes play important roles in the cellular energy metabolism of animals. Biochemical, physiological and molecular information with respect to lombricine... | Amino Acid Sequence, Animals, Base Sequence, Evolution, Molecular, Exons, Genetic Variation, Introns, Molecular Sequence Data, Oligochaeta, Phosphotransferases (Nitrogenous Group Acceptor), Phylogeny, Sequence Alignment | null |
22,705,028 | 2013-04-08 | 2022-03-10 | 1873-2933 | Clinical biochemistry | Performance evaluation of Siemens ADVIA Centaur and Roche MODULAR Analytics E170 Total 25-OH Vitamin D assays. | Chen Yu, Kinney Lois, Božović Andrea, Smith Hilary, Tarr Heather, Diamandis Eleftherios P, LeBlanc Adrien | eng | Z99 CL999999 (Intramural NIH HHS, United States); ZIA CL010355-01 (Intramural NIH HHS, United States) | Comparative Study, Evaluation Study, Journal Article | Ergocalciferols, Cholecalciferol | IM | 22705028, S0009-9120(12)00271-8, 10.1016/j.clinbiochem.2012.06.002, PMC4193681, NIHMS632834, 22247500, 22244986, 19563791, 20026023, 22238254, 18325178, 20601202, 21566493, 19109939, 22391026, 21348404, 20302938, 21646368, 21601563, 22411495, 17846391, 20795940, 19631201, 22334482, 22141317, 21646873, 18179991, 2014206... | To evaluate the newly developed Roche MODULAR Analytics E170 Total Vitamin D and the Siemens ADVIA Centaur Vitamin D Total assays. | Blood Chemical Analysis, Cholecalciferol, Ergocalciferols, Humans, Limit of Detection, Linear Models, Reference Standards, Signal-To-Noise Ratio, Tandem Mass Spectrometry | null |
22,705,029 | 2013-03-12 | 2019-12-10 | 1768-3122 | La Revue de medecine interne | [Crushing drugs in geriatric units: an "handicraft" practice with frequent errors which imposed recommendations]. | Caussin M, Mourier W, Philippe S, Capet C, Adam M, Reynero N, Jouini C, Colombier A-S, Kadri K, Landrin I, Gréboval E, Rémy E, Marc F, Touflet M, Wirotius F, Delabre N, Le Hiress C, Rorteau V, Vimard M, Dufour M, Tharasse C, Dieu B, Varin R, Doucet J | fre | null | Evaluation Study, Journal Article | Capsules, Dosage Forms, Pharmaceutical Preparations | IM | 22705029, S0248-8663(12)00530-9, 10.1016/j.revmed.2012.05.014 | Swallowing disorders or psycho-behavioural distress frequently interfere on drug administration in elderly inpatients. Crushing drugs is a common although non validated practice. The objective of this first prospective study, performed in all geriatric units of the Rouen university hospital by a multidisciplinary group... | Administration, Oral, Aged, Aged, 80 and over, Capsules, Deglutition Disorders, Dosage Forms, Female, Geriatrics, Humans, Iatrogenic Disease, Incidence, Male, Medication Errors, Pharmaceutical Preparations, Practice Guidelines as Topic, Professional Practice | null |
22,705,030 | 2013-05-17 | 2016-10-18 | 1768-3122 | La Revue de medecine interne | [Epidemiology and management of isolated distal deep venous thrombosis]. | Galanaud J-P, Kahn S R, Khau Van Kien A, Laroche J-P, Quéré I | fre | null | English Abstract, Journal Article, Review | Anticoagulants | IM | 22705030, S0248-8663(12)00528-0, 10.1016/j.revmed.2012.05.012 | Isolated distal deep-vein thromboses (DVT) are infra-popliteal DVT without involvement of proximal veins or pulmonary embolism (PE). They can affect deep calf (tibial anterior, tibial posterior, or peroneal) or muscular (gastrocnemius or soleal) veins. They represent half of all lower limbs DVT. Proximal and distal DVT... | Anticoagulants, Humans, Leg, Lower Extremity, Models, Biological, Prevalence, Risk Factors, Venous Thrombosis | null |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.