text stringlengths 0 197k |
|---|
We aim to 1) quantify the impact of PERSEVERE on caregiver knowledge, attitudes, mastery, and strain; 2) identify the intervention and mentor factors determining implementation fidelity; and 3) test the effects of PERSEVERE on PLBD quality of life and healthcare utilization. This will be accomplished in an NIH Behavior... |
<|newrecord|> nctId: NCT06389019 id: BLCA_CMUFH id: K2024-187-01 type: OTHER domain: The First Affiliated Hospital of Chongqing Medical University briefTitle: Whole-slide Image and CT Radiomics Based Deep Learning System for Prognostication Prediction in Bladder Cancer overallStatus: RECRUITING date: 2024-01-01 date: 2... |
<|newrecord|> nctId: NCT06389006 id: RC48-C025 briefTitle: To Evaluate the Efficacy and Safety of Disitamab Vedotin Combined With Toripalimab Sequential Chemotherapy as Neoadjuvant Treatment in Patients With HR-positive, HER2-low Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2025-06-01 date: 20... |
<|newrecord|> nctId: NCT06388993 id: 2023H0351 briefTitle: Marrow Cellution™ vs. Traditional BMA Harvest Project overallStatus: RECRUITING date: 2024-03-25 date: 2024-12-31 date: 2025-03-31 date: 2024-04-29 date: 2024-04-29 name: Ohio State University class: OTHER briefSummary: Six patients with diagnosed bone loss of ... |
<|newrecord|> nctId: NCT06388980 id: UFCIN1_2022 briefTitle: Knowledge and Needs of Nursing in Relation to the Treatment Complex Wounds overallStatus: ACTIVE_NOT_RECRUITING date: 2023-05-01 date: 2023-06-01 date: 2024-06-01 date: 2024-04-29 date: 2024-04-29 name: Corporacion Parc Tauli class: OTHER briefSummary: Study ... |
<|newrecord|> nctId: NCT06388967 id: 19288/PCDC briefTitle: Pancreatic Cancer Detection Consortium acronym: PCDC overallStatus: RECRUITING date: 2023-03-15 date: 2025-11-21 date: 2025-11-21 date: 2024-04-29 date: 2024-04-29 name: City of Hope Medical Center class: OTHER briefSummary: This study aims to prospective vali... |
<|newrecord|> nctId: NCT06388954 id: P.T.REC/012/005107 briefTitle: Plasticity Biomarkers,Interleukin-6 and Motor Performance in Response to Vagus Nerve Stimulation After Stroke overallStatus: RECRUITING date: 2024-02-21 date: 2024-04-23 date: 2024-05-09 date: 2024-04-29 date: 2024-04-29 name: Cairo University class: O... |
<|newrecord|> nctId: NCT06388941 id: CLNP023R12201 briefTitle: Iptacopan in Patients With ANCA Associated Vasculitis overallStatus: NOT_YET_RECRUITING date: 2024-08-28 date: 2027-08-27 date: 2027-09-22 date: 2024-04-29 date: 2024-04-29 name: Novartis Pharmaceuticals class: INDUSTRY briefSummary: The purpose of this stu... |
<|newrecord|> nctId: NCT06388928 id: P.T.REC/012/004596 briefTitle: Effect of Menstrual Cycle on the Manual Dexterity of Female Dentists overallStatus: COMPLETED date: 2023-07-09 date: 2023-12-26 date: 2023-12-26 date: 2024-04-29 date: 2024-04-29 name: Cairo University class: OTHER briefSummary: The aim of this observa... |
This study was conducted to answer the following question: |
- Is there any effect of the menstrual cycle on the manual dexterity of female dentists? conditions: Menstrual Cycle conditions: Manual Dexterity studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 45 type: ACTUAL measure: Manual dexterity assessment sex: FEMALE minimumAge: 25 Yea... |
<|newrecord|> nctId: NCT06388915 id: K2202403004 briefTitle: A Retrospective Cohort Study of 15 Cases of Pelvic Fractures Complicated by Morel-Lavallee Lesion overallStatus: COMPLETED date: 2024-03-12 date: 2024-03-20 date: 2024-03-23 date: 2024-04-29 date: 2024-04-29 name: Weikang Chen class: OTHER briefSummary: Some ... |
<|newrecord|> nctId: NCT06388902 id: BR115-101 briefTitle: A Phase I Study of BR115 for Injection Alone in Subjects With Advanced Solid Malignancies overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-08 date: 2028-12 date: 2024-04-29 date: 2024-04-29 name: BioRay Pharmaceutical Co., Ltd. class: INDUSTRY briefSu... |
Patients will receive two doses at the first week of treatment, followed by once per week until intolerable toxicity, disease progression, pregnancy, withdrawal of informed consent, death, study discontinuation, or withdrawal from the study. conditions: Advanced Solid Malignancies studyType: INTERVENTIONAL phases: PHAS... |
<|newrecord|> nctId: NCT06388889 id: AR-DEX-22-04 briefTitle: Phase III Long-Term Extension Study With Dexpramipexole acronym: EXHALE-5 overallStatus: ENROLLING_BY_INVITATION date: 2024-05-08 date: 2027-06-01 date: 2027-06-01 date: 2024-04-29 date: 2024-04-29 name: Areteia Therapeutics class: INDUSTRY briefSummary: The... |
<|newrecord|> nctId: NCT06388876 id: AnkaraYBUbk briefTitle: The Effect of Exercise on Post-traumatic Stress Disorder and Sleep Quality in Individuals Affected by the 2023 Kahramanmaraş Earthquakes overallStatus: COMPLETED date: 2023-04-01 date: 2023-06-15 date: 2023-07-30 date: 2024-04-29 date: 2024-04-29 name: Ankara... |
<|newrecord|> nctId: NCT06388863 id: B2024-002 briefTitle: Evaluation of the Efficacy and Safety of FMT for Constipation in Parkinson's Disease overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-05-31 date: 2026-05-31 date: 2024-04-29 date: 2024-04-29 name: Shanghai Zhongshan Hospital class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06388850 id: 5U01CE003393-03 type: NIH link: https://reporter.nih.gov/quickSearch/5U01CE003393-03 briefTitle: Evaluation of HRP Among Pre-K Through 5th Grade overallStatus: ENROLLING_BY_INVITATION date: 2023-03-23 date: 2025-09-30 date: 2025-09-30 date: 2024-04-29 date: 2024-04-29 name: Northeas... |
<|newrecord|> nctId: NCT06388837 id: RECO6U/20- 2021 briefTitle: Effect of Symphysis Onlay Bone Graft, Injectable Platelet Rich Fibrin (I-PRF) and Xenograft on Horizontal Alveolar Ridge Augmentation in Esthetic Zone overallStatus: COMPLETED date: 2021-02-20 date: 2023-03-01 date: 2023-03-01 date: 2024-04-29 date: 2024-... |
<|newrecord|> nctId: NCT06388824 id: GWang028 briefTitle: The Effect of Esketamine on Sleep Disturbance overallStatus: NOT_YET_RECRUITING date: 2024-05-20 date: 2024-09-30 date: 2024-10-10 date: 2024-04-29 date: 2024-04-29 name: Tianjin Medical University General Hospital class: OTHER briefSummary: To explore the effic... |
<|newrecord|> nctId: NCT06388811 id: 2023/1162 briefTitle: Validity and Reliability Study of the Turkish Version of the Early Osteoarthritis Questionnaire overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2024-11-15 date: 2024-12-15 date: 2024-04-29 date: 2024-04-29 name: Istanbul University class: OTHER briefSu... |
Therefore, the assessment of early knee OA with a questionnaire may facilitate the follow-up of OA in the early stages of the disease when treatment is likely to be more effective. This approach will allow to reduce disability and improve patients' quality of life. While creating the Early Osteoarthritis Questionnaire ... |
For the translation of the questionnaire, the guide recommended by Beaton et al. for the cultural adaptation of questionnaires will be used. According to this guideline the original EOAQ will be translated into Turkish by two experts independently of each other, and then a single Turkish version will be created by two ... |
<|newrecord|> nctId: NCT06388798 id: Ankara Etlik city hospital briefTitle: Evaluation of the Effectiveness of Psychoeducational Training Given to Nurses Working in a Psychiatric Clinic overallStatus: COMPLETED date: 2023-05-30 date: 2023-07-30 date: 2023-07-30 date: 2024-04-29 date: 2024-04-29 name: Ankara Etlik City ... |
Background One of the most important roles of psychiatric nurses, who help individuals, families and society in promoting health, preventing diseases and coping with problems, is their educational role. With its educational role, the nurse can help the patient and their family function at the best level in biopsychosoc... |
Goals This research was conducted to evaluate the effectiveness of psychoeducational training given to nurses working in a psychiatric clinic. |
Design This research is a randomized controlled experimental study. Participants Participants were determined using simple randomization. The sample of the study consisted of 78 nurses (intervention = 39; control = 39) working in a psychiatric clinic in a city hospital in Turkey. |
Methods Groups were determined using the simple randomization method. Psychoeducational training was given to the intervention group, nurses working in the Psychiatry clinic, for a total of 4 sessions, with two sessions of 50 minutes each. The data of the research were collected with the ;Personal Information Form; For... |
<|newrecord|> nctId: NCT06388785 id: TAK-003-5001 briefTitle: A Study to Monitor the Adverse Events of QDENGA Vaccine in Participants in Malaysia acronym: PRIME-Q overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2027-09-01 date: 2027-09-01 date: 2024-04-29 date: 2024-04-29 name: Takeda class: INDUSTRY briefSumm... |
No vaccination will be given as part of this study. The study will only collect data of persons already vaccinated with QDENGA who agree to participate. conditions: Dengue Fever studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 10000 type: ESTIMATED name: No Intervention measure: N... |
<|newrecord|> nctId: NCT06388772 id: HJG-CZQH-QHRD106 briefTitle: Study to Assess PK, Safety and Tolerability Early in Healthy Subjects overallStatus: COMPLETED date: 2021-07-05 date: 2022-07-22 date: 2023-01-06 date: 2024-04-29 date: 2024-04-29 name: Changzhou Qianhong Bio-pharma Co., Ltd. class: INDUSTRY briefSummary... |
<|newrecord|> nctId: NCT06388759 id: TQ05105-Ib-03 briefTitle: TQ05105 Tablet for Myelofibrosis Treatment in Ruxolitinib-Resistant or Intolerant Patients overallStatus: ACTIVE_NOT_RECRUITING date: 2022-08-01 date: 2024-12 date: 2024-12 date: 2024-04-29 date: 2024-04-29 name: Chia Tai Tianqing Pharmaceutical Group Co., ... |
<|newrecord|> nctId: NCT06388746 id: NKUA briefTitle: Arresting Carious Lesions With Minimal Intervention Techniques overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-06 date: 2025-12 date: 2024-04-29 date: 2024-04-29 name: National and Kapodistrian University of Athens class: OTHER briefSummary: A single-blin... |
<|newrecord|> nctId: NCT06388733 id: IVY P3-24-021 briefTitle: A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2027-12 date: 2028-03 date: 2024-04-29 date: 2024-04-29 name: Ivy Brain Tumor Cent... |
Does niraparib improve progression-free survival (PFS) compared to TMZ? |
Does niraparib improve overall survival (OS) compared to TMZ? |
Participants will be randomly assigned to one of two treatment arms: niraparib or TMZ. |
* study drug (Niraparib) or |
* comparator drug (Temozolomide - which is the standard approved treatment for MGMT unmethylated glioblastoma). |
The study medication will be taken daily while receiving standard of care radiation therapy (RT) for 6-7 weeks. |
Participants may continue to take the niraparib or TMZ adjuvantly as long as the cancer does not get worse or completion of 6 cycles of treatment (TMZ). A total of 450 participants will be enrolled in the study. |
Participants' tasks will include: |
* Complete study visits as scheduled |
* Complete a diary to record study medication conditions: Glioblastoma conditions: GBM conditions: Brain Neoplasms, Adult, Malignant conditions: Brain Tumor studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE maskingDescription: Blinded Ind... |
<|newrecord|> nctId: NCT06388720 id: NCC2024-0026 briefTitle: The Clinical Effectiveness and Safety of Intravesical Mitomycin-C and Gemcitabine Sequential Therapy acronym: IMGeS overallStatus: RECRUITING date: 2024-04-30 date: 2025-06-30 date: 2027-12-31 date: 2024-04-29 date: 2024-04-29 name: National Cancer Center, K... |
<|newrecord|> nctId: NCT06388707 id: NF-2022-01 briefTitle: A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2025-07-31 date: 2025-12-31 date: 2024-04-29 date: 2024-04-29... |
<|newrecord|> nctId: NCT06388694 id: RDO KPNC 24-056 briefTitle: Pharmacist Management of Attention Deficit Hyperactivity Disorder Medication Refill Requests overallStatus: NOT_YET_RECRUITING date: 2024-05-02 date: 2024-06-28 date: 2024-07-31 date: 2024-04-29 date: 2024-04-29 name: Kaiser Permanente class: OTHER briefS... |
<|newrecord|> nctId: NCT06388681 id: HMKU-KMY-SA-02 briefTitle: Stress Ball Use in Patients Undergoing Coronary Angiography overallStatus: RECRUITING date: 2024-04-24 date: 2024-04-26 date: 2024-06-26 date: 2024-04-29 date: 2024-04-29 name: Mustafa Kemal University class: OTHER briefSummary: One of the nonpharmacologic... |
<|newrecord|> nctId: NCT06388668 id: ICM 2025-3428 briefTitle: Lipid Testing After Myocardial Infarction at the Montreal Heart Institute overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-07 date: 2025-09 date: 2024-04-29 date: 2024-04-29 name: Montreal Heart Institute class: OTHER name: Novartis Pharmaceutical... |
It will be a single-center, prospective, observational study will be conducted, including consecutive patients hospitalized for myocardial infarction at the Montreal Heart Institute. |
Every patient at the Cardiac Care Unit will undergo non-fasting lipid panel testing at day 0 of their admission for Myocardial Infarction during the study period. Patients who consent to participate will have a 2nd non-fasting lipid panel drawn at day 2 of their admission. |
Thereafter, the levels of the different lipid values from the panel will be compared between day 0, day 2, and 4-6 weeks after discharge. conditions: Dyslipidemias conditions: Lipid Testing conditions: Myocardial Infarction studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 100 t... |
<|newrecord|> nctId: NCT06388655 id: MDCR-19-007 briefTitle: The Effect of the Mobile EEG-Neurofeedback in Healthy Child and Adolescent overallStatus: COMPLETED date: 2019-06-10 date: 2022-06-30 date: 2022-06-30 date: 2024-04-29 date: 2024-04-29 name: Daegu Catholic University Medical Center class: OTHER briefSummary: ... |
<|newrecord|> nctId: NCT06388642 id: CUV052 briefTitle: Pharmacokinetics of Afamelanotide in EPP Patients overallStatus: RECRUITING date: 2024-03-07 date: 2024-07-01 date: 2024-10-01 date: 2024-04-29 date: 2024-04-29 name: Clinuvel Europe Limited class: INDUSTRY briefSummary: The purpose of this study is to evaluate th... |
<|newrecord|> nctId: NCT06388629 id: M064-066 Rev 00 briefTitle: Epicardial Access Study With Rook acronym: EASY-R overallStatus: RECRUITING date: 2023-12-17 date: 2024-05 date: 2024-05 date: 2024-04-29 date: 2024-04-29 name: Circa Scientific, Inc. class: INDUSTRY briefSummary: The goal of this clinical trial is to tes... |
Participants will receive treatment with the subject device during the course of a typical epicardial electrophysiology procedure. conditions: Arrythmia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Prospective, non-randomized primaryPurpose: OTHER mas... |
<|newrecord|> nctId: NCT06388616 id: D6402C00013 briefTitle: Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone overallStatus: NOT_YET_RECRUITING date: 2024-05-02 date: 2024-11-15 date: 2024-11-15 date: 2024-04-29 date: 2024-04-29 name: AstraZeneca cl... |
All subjects will receive the study intervention: |
* Cohort 1 will enroll 8 participants with mild hepatic impairment |
* Cohort 2 will enroll 8 participants with moderate hepatic impairment |
* Cohort 3 will enroll 8-12 healthy participants matched on a group level regarding age, BMI and sex primaryPurpose: TREATMENT masking: NONE count: 28 type: ESTIMATED name: Balcinrenone measure: Area under plasma concentration-time curve from time zero to the last measurable concentration (AUClast) measure: Area under ... |
<|newrecord|> nctId: NCT06388603 id: DFORCT012023 briefTitle: RCT on Bioactive Glass S53P4 in Diabetic Foot Osteomyelitis in the Forefoot (DFORCT) acronym: DFORCT overallStatus: RECRUITING date: 2024-03-21 date: 2026-09-30 date: 2026-12-30 date: 2024-04-29 date: 2024-04-29 name: ASST Ovest Milanese class: OTHER name: H... |
Participants will randomized into two groups: |
* Patients in Group A will be treated with surgical removal of the affected bone, debridement of infected soft tissues and systemic antibiotic therapy targeted on the sampling on the bone during the surgical procedure, with or without use of bone substitutes (with the only exception of Bioactive glasses) according to t... |
* Patients in Group B will be debrided as well and the infected bone will be debrided without eliminating completely the structure of the bone, but instead preserving the cortex, while all the soft bone visibly infected will be removed and then replaced with Bioactive glass, as per IFU, (S53P4 - Bonalive® granules and ... |
<|newrecord|> nctId: NCT06388590 id: MOMMC.2024.0029 briefTitle: Acupuncture for Chronic Pelvic Pain overallStatus: RECRUITING date: 2024-04 date: 2026-04 date: 2026-04 date: 2024-04-29 date: 2024-04-29 name: David Moss class: FED briefSummary: The objective of this study is to determine if alternative pain management ... |
This study may support evidence for an inexpensive alternative means of treatment for patients with or without traumatic sexual history and chronic pelvic pain. conditions: Pelvic Pain conditions: Acupuncture conditions: Gynecology studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: CROSS... |
<|newrecord|> nctId: NCT06388577 id: MEU-HEM-SY-189 briefTitle: The Effect of the Training Programme Based on the Health Promotion Model Given to Parents overallStatus: NOT_YET_RECRUITING date: 2024-05-13 date: 2024-06-13 date: 2024-09-13 date: 2024-04-29 date: 2024-04-29 name: Mersin University class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06388564 id: INCA34176-254 id: 2022-502168-19-00 type: REGISTRY domain: EU CT Number briefTitle: A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease overallStatus: NOT_YET_RECRUITING date... |
<|newrecord|> nctId: NCT06388551 id: LY03017/CT-CHN-101 briefTitle: A Phase 1, SAD Study to Evaluate the Safety and Tolerability of LY03017 overallStatus: NOT_YET_RECRUITING date: 2024-05-10 date: 2025-03-30 date: 2025-03-30 date: 2024-04-29 date: 2024-04-29 name: Luye Pharma Group Ltd. class: INDUSTRY briefSummary: Th... |
<|newrecord|> nctId: NCT06388538 id: Carlo Bergamini briefTitle: The COLD2B Multicenter, Two-arm Prospective Cohort Study acronym: COLD2B overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-05-01 date: 2025-06-01 date: 2024-04-29 date: 2024-04-29 name: Azienda Sanitaria di Firenze class: OTHER briefSummary: S... |
The primary aim of the COLD2B (Conservative vs surgical (either Open or Laparoscopic) approach in the emergency management of acute Diverticulitis WSES 2B) study is to develop a model able to predict the length of hospitalization, comparing the management of WSES 2b AD in the emergency setting (conservative versus surg... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.