AgentSLR: Automating Systematic Literature Reviews in Epidemiology with Agentic AI
Paper • 2603.22327 • Published • 10
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PMID_19132113 | Both | 19,132,113 | PMC2164958 | 10.1242/dmm.000471 | Disease modeling for Ebola and Marburg viruses | Dennis A. Bente; Jason Gren; James E. Strong; Heinz Feldmann | Disease Models & Mechanisms | 2,009 | The filoviruses Ebola and Marburg are zoonotic agents that are classified as both biosafety level 4 and category A list pathogens. These viruses are pathogenic in humans and cause isolated infections or epidemics of viral hemorrhagic fever, mainly in Central Africa. Their natural reservoir has not been definitely ident... | https://pubmed.ncbi.nlm.nih.gov/19132113/ | https://openalex.org/W1975525323 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #2799 | true |
PMID_27887599 | OpenAlex | 27,887,599 | null | 10.1186/s12879-016-2045-6 | How severe and prevalent are Ebola and Marburg viruses? A systematic review and meta-analysis of the case fatality rates and seroprevalence | Luke Nyakarahuka; Clovice Kankya; Randi Krontveit; Benjamin Mayer; Frank Norbert Mwiine; Julius J. Lutwama; Eystein Skjerve | BMC Infectious Diseases | 2,016 | The pooled CFR and seroprevalence for Ebola and Marburg viruses were found to be lower than usually reported, with species differences despite high heterogeneity between studies. Countries with an improved health surveillance and epidemic response have lower CFR, thereby indicating need for improving early detection an... | https://pubmed.ncbi.nlm.nih.gov/27887599/ | https://openalex.org/W2554930001 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | null | null | null | false |
PMID_19785757 | OpenAlex | 19,785,757 | null | 10.1186/1471-2334-9-159 | Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus | Xavier Pourrut; Marc Souris; Jonathan S. Towner; Pierre E. Rollin; Stuart T. Nichol; Jean‐Paul Gonzalez; Eric M. Leroy | BMC Infectious Diseases | 2,009 | These findings confirm that ZEBOV and MARV co-circulate in Gabon, the only country where bats infected by each virus have been found. IgG antibodies to both viruses were detected only in Rousettus aegyptiacus, suggesting that this bat species may be involved in the natural cycle of both Marburg and Ebola viruses. The p... | https://pubmed.ncbi.nlm.nih.gov/19785757/ | https://openalex.org/W1985699976 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1828 | true |
PMID_24046765 | OpenAlex | 24,046,765 | null | 10.3389/fmicb.2013.00267 | Animal models for Ebola and Marburg virus infections | Eri Nakayama; Masayuki Saijo | Frontiers in Microbiology | 2,013 | Ebola and Marburg hemorrhagic fevers (EHF and MHF) are caused by the Filoviridae family, Ebolavirus and Marburgvirus (ebolavirus and marburgvirus), respectively. These severe diseases have high mortality rates in humans. Although EHF and MHF are endemic to sub-Saharan Africa. A novel filovirus, Lloviu virus, which is g... | https://pubmed.ncbi.nlm.nih.gov/24046765/ | https://openalex.org/W2079928928 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1965 | true |
PMID_26063223 | OpenAlex | 26,063,223 | null | 10.1093/infdis/jiv284 | Considerations in the Use of Nonhuman Primate Models of Ebola Virus and Marburg Virus Infection: Table 1. | Thomas W. Geisbert; James E. Strong; Heinz Feldmann | The Journal of Infectious Diseases | 2,015 | The filoviruses, Ebola virus and Marburg virus, are zoonotic pathogens that cause severe hemorrhagic fever in humans and nonhuman primates (NHPs), with case-fatality rates ranging from 23% to 90%. The current outbreak of Ebola virus infection in West Africa, with >26 000 cases, demonstrates the long-underestimated publ... | https://pubmed.ncbi.nlm.nih.gov/26063223/ | https://openalex.org/W2108356414 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #3773 | true |
PMID_28194016 | Both | 28,194,016 | PMC3879242 | 10.1038/ncomms14446 | Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats | Amy J. Schuh; Brian R. Amman; Megan Jones; Tara K. Sealy; Luke S. Uebelhoer; Jessica R. Spengler; Brock E. Martin; Jo Ann D. Coleman-McCray; Stuart T. Nichol; Jonathan S. Towner | Nature Communications | 2,017 | Abstract The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV); however, the mechanisms by which MARV is transmitted bat-to-bat and to other animals are unclear. Here we co-house MARV-inoculated donor ERBs with naive contact ERBs. MARV shedding is detected in oral, rectal and urine specim... | https://pubmed.ncbi.nlm.nih.gov/28194016/ | https://openalex.org/W2588838495 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1755 | true |
PMID_31888676 | OpenAlex | 31,888,676 | null | 10.1186/s12985-019-1272-z | Marburg virus pathogenesis – differences and similarities in humans and animal models | Kyle Shifflett; Andrea Marzi | Virology Journal | 2,019 | Abstract Marburg virus (MARV) is a highly pathogenic virus associated with severe disease and mortality rates as high as 90%. Outbreaks of MARV are sporadic, deadly, and often characterized by a lack of resources and facilities to diagnose and treat patients. There are currently no approved vaccines or treatments, and ... | https://pubmed.ncbi.nlm.nih.gov/31888676/ | https://openalex.org/W2997158122 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #5678 | true |
PMID_38040006 | Both | 38,040,006 | PMC6050668 | 10.1016/s1473-3099(23)00515-7 | Marburg virus disease outbreaks, mathematical models, and disease parameters: a systematic review | Gina Cuomo-Dannenburg; Kelly McCain; Ruth McCabe; H. Juliette T. Unwin; Patrick Doohan; Rebecca K. Nash; Joseph T. Hicks; Kelly Charniga; Cyril Geismar; Ben Lambert; Dariya Nikitin; Janetta Skarp; Jack Wardle; Mara D. Kont; Sangeeta Bhatia; Natsuko Imai; Sabine van Elsland; Anne Cori; Christian Morgenstern; Aaron Morri... | The Lancet Infectious Diseases | 2,023 | The 2023 Marburg virus disease outbreaks in Equatorial Guinea and Tanzania highlighted the importance of better understanding this lethal pathogen. We did a systematic review (PROSPERO CRD42023393345) of peer-reviewed articles reporting historical outbreaks, modelling studies, and epidemiological parameters focused on ... | https://pubmed.ncbi.nlm.nih.gov/38040006/ | https://openalex.org/W4389074224 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | null | null | null | false |
PMID_25392474 | OpenAlex | 25,392,474 | null | 10.1098/rspb.2014.2124 | Ecological dynamics of emerging bat virus spillover | Raina K. Plowright; Peggy Eby; Peter J. Hudson; Ina Smith; David A. Westcott; W. L. Bryden; Deborah Middleton; Peter A. Reid; R. A. McFarlane; Gerardo Martín; Gary Tabor; Lee F. Skerratt; Dale L. Anderson; Gary Crameri; David Quammen; David Jordan; P. H. Freeman; Lin‐Fa Wang; Jonathan H. Epstein; Glenn A. Marsh; Nina K... | Proceedings of the Royal Society B Biological Sciences | 2,014 | Viruses that originate in bats may be the most notorious emerging zoonoses that spill over from wildlife into domestic animals and humans. Understanding how these infections filter through ecological systems to cause disease in humans is of profound importance to public health. Transmission of viruses from bats to huma... | https://pubmed.ncbi.nlm.nih.gov/25392474/ | https://openalex.org/W2096136553 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1836 | true |
PMID_37771708 | OpenAlex | 37,771,708 | null | 10.3389/fmicb.2023.1239079 | Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges | Shriyansh Srivastava; Deepika Sharma; Sachin Kumar; Aditya Kumar Sharma; Rishikesh Rijal; Ankush Asija; Suraj Adhikari; Sarvesh Rustagi; Sanjit Sah; Zahraa Haleem Al‐qaim; Prashant Bashyal; Aroop Mohanty; Joshuan J. Barboza; Alfonso J. Rodríguez‐Morales; Ranjit Sah | Frontiers in Microbiology | 2,023 | The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus strain, but the average case fatality rate is around 50%. However, case fatality rates have varied from 24 to 88% in past outbreaks depending on... | https://pubmed.ncbi.nlm.nih.gov/37771708/ | https://openalex.org/W4386784428 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | null | null | null | false |
PMID_16943403 | Both | 16,943,403 | null | 10.1056/nejmoa051465 | Marburg Hemorrhagic Fever Associated with Multiple Genetic Lineages of Virus | Daniel G. Bausch; Stuart T. Nichol; Jean Jacques Muyembe-Tamfum; Matthias Borchert; Pierre E. Rollin; Hilde Sleurs; Patricia T. Campbell; F. Kweteminga Tshioko; Catherine Roth; Robert Colebunders; Patricia Pirard; S Mardel; Loku Abisa Olinda; H. Zeller; Antoine Tshomba; Amayo Kulidri; Modeste L. Libande; Sabue Mulangu;... | New England Journal of Medicine | 2,006 | Marburg hemorrhagic fever can have a very high case fatality rate. Since multiple genetic variants of virus were identified, ongoing introduction of virus into the population helped perpetuate this outbreak. The findings imply that reservoir hosts of Marburg virus inhabit caves, mines, or similar habitats. | https://pubmed.ncbi.nlm.nih.gov/16943403/ | https://openalex.org/W2081913810 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | INCLUDE | INCLUDE | #2819 | true |
PMID_9254917 | Both | 9,254,917 | null | 10.1093/oxfordjournals.molbev.a025820 | The origin and evolution of Ebola and Marburg viruses | Yasuo Suzuki; Takashi Gojobori | Molecular Biology and Evolution | 1,997 | Molecular evolutionary analyses for Ebola and Marburg viruses were conducted with the aim of elucidating evolutionary features of these viruses. In particular, the rate of nonsynonymous substitutions for the glycoprotein gene of Ebola virus was estimated to be, on the average, 3.6 x 10(-5) per site per year. Marburg vi... | https://pubmed.ncbi.nlm.nih.gov/9254917/ | https://openalex.org/W2121586109 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | INCLUDE | INCLUDE | #1649 | true |
PMID_26306510 | OpenAlex | 26,306,510 | null | 10.1186/s12862-015-0456-4 | Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution | Izza Nasrullah; Azeem Mehmood Butt; Shifa Tahir; Muhammad Idrees; Yigang Tong | BMC Evolutionary Biology | 2,015 | Abstract Background The Marburg virus (MARV) has a negative-sense single-stranded RNA genome, belongs to the family Filoviridae , and is responsible for several outbreaks of highly fatal hemorrhagic fever. Codon usage patterns of viruses reflect a series of evolutionary changes that enable viruses to shape their surviv... | https://pubmed.ncbi.nlm.nih.gov/26306510/ | https://openalex.org/W1926697416 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1959 | true |
PMID_307456 | Both | 307,456 | PMC2395567 | 10.11619/africa1964.1996.49_95 | Ebola haemorrhagic fever in Zaire | Sinroku Otatume | Journal of African Studies | 1,996 | Between 1 September and 24 October 1976, 318 cases of acute viral haemorrhagic fever occurred in northern Zaire. The outbreak was centred in the Bumba Zone of the Equateur Region and most of the cases were recorded within a radius of 70 km of Yambuku, although a few patients sought medical attention in Bumba, Abumombaz... | https://pubmed.ncbi.nlm.nih.gov/307456/ | https://openalex.org/W1987080862 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #2916 | true |
PMID_25375951 | Both | 25,375,951 | PMC2713404 | 10.7589/2014-08-198 | ORAL SHEDDING OF MARBURG VIRUS IN EXPERIMENTALLY INFECTED EGYPTIAN FRUIT BATS ( <i>ROUSETTUS AEGYPTIACUS</i> ) | Brian R. Amman; Megan Jones; Tara K. Sealy; Luke S. Uebelhoer; Amy J. Schuh; Brian H. Bird; JoAnn D. Coleman-McCray; Brock E. Martin; Stuart T. Nichol; Jonathan S. Towner | Journal of Wildlife Diseases | 2,014 | Marburg virus (Marburg marburgvirus; MARV) causes sporadic outbreaks of Marburg hemorrhagic fever (MHF) in Africa. The Egyptian fruit bat (Rousettus aegyptiacus) has been identified as a natural reservoir based most-recently on the repeated isolation of MARV directly from bats caught at two locations in southwestern Ug... | https://pubmed.ncbi.nlm.nih.gov/25375951/ | https://openalex.org/W2135335521 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #2868 | true |
PMID_569445 | Both | 569,445 | null | 10.4269/ajtmh.1978.27.1210 | Epidemiologic Investigation of Marburg Virus Disease, Southern Africa, 1975 | Jonas Conrad; M Isaäcson; Eric Burnett Smith; Herta Wulff; Megan Crees; Piet Geldenhuys; James C. Johnston | American Journal of Tropical Medicine and Hygiene | 1,978 | During the first 10 days of February 1975, an Australian hitchhiker contracted Marburg virus disease while traveling through Rhodesia and died; the infection was subsequently passed to two other persons, who recovered. Investigators retraced the hitchhiker's steps in March and again in June 1975 in an effort to uncover... | https://pubmed.ncbi.nlm.nih.gov/569445/ | https://openalex.org/W28508157 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | INCLUDE | INCLUDE | #2573 | true |
PMID_25142608 | OpenAlex | 25,142,608 | null | 10.1128/jvi.01643-14 | Establishment and Characterization of a Lethal Mouse Model for the Angola Strain of Marburg Virus | Xiangguo Qiu; Jonathan Audet; Todd Cutts; Yulian Niu; Stephanie A. Booth; Gary Wong; Gary P. Kobinger | Journal of Virology | 2,014 | ABSTRACT Infections with Marburg virus (MARV) and Ebola virus (EBOV) cause severe hemorrhagic fever in humans and nonhuman primates (NHPs) with fatality rates up to 90%. A number of experimental vaccine and treatment platforms have previously been shown to be protective against EBOV infection. However, the rate of deve... | https://pubmed.ncbi.nlm.nih.gov/25142608/ | https://openalex.org/W2004688512 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1821 | true |
PMID_23055920 | Both | 23,055,920 | PMC3203392 | 10.1371/journal.ppat.1002877 | Seasonal Pulses of Marburg Virus Circulation in Juvenile Rousettus aegyptiacus Bats Coincide with Periods of Increased Risk of Human Infection | Brian R. Amman; Serena A. Carroll; Zachary Reed; Tara K. Sealy; Stephen Balinandi; Robert Swanepoel; Alan C. Kemp; Bobbie R. Erickson; James A. Comer; Shelley Campbell; Deborah Cannon; Marina L. Khristova; Patrick Atimnedi; Christopher D. Paddock; Rebekah J. Kent Crockett; Timothy D. Flietstra; Kelly L. Warfield; Rober... | PLoS Pathogens | 2,012 | Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases among miners infected in 2007 at the Kitaka mine, Uganda, which contained a large population of M... | https://pubmed.ncbi.nlm.nih.gov/23055920/ | https://openalex.org/W2131851182 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | INCLUDE | INCLUDE | #2869 | true |
PMID_30202878 | OpenAlex | 30,202,878 | null | 10.1093/infdis/jiy435 | Infection Rates and Risk Factors for Infection Among Health Workers During Ebola and Marburg Virus Outbreaks: A Systematic Review | Saranya Selvaraj; Karen Lee; Mason Harrell; Ivan Ivanov; Benedetta Allegranzi | The Journal of Infectious Diseases | 2,018 | Many outbreaks reported high proportions of infected HWs. Similar HW infection rates and exposure risk factors in both past and recent EVD and MVD outbreaks emphasize the need to improve the implementation of appropriate infection control measures consistently across all healthcare settings. | https://pubmed.ncbi.nlm.nih.gov/30202878/ | https://openalex.org/W2890805251 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #1737 | true |
PMID_17712412 | Both | 17,712,412 | PMC1488971 | 10.1371/journal.pone.0000764 | Marburg Virus Infection Detected in a Common African Bat | Jonathan S. Towner; Xavier Pourrut; César G. Albariño; Chimène Nze-Nkogue; Brian H. Bird; Gilda Grard; Thomas G. Ksiazek; Jean‐Paul Gonzalez; Stuart T. Nichol; Eric M. Leroy | PLoS ONE | 2,007 | Marburg and Ebola viruses can cause large hemorrhagic fever (HF) outbreaks with high case fatality (80-90%) in human and great apes. Identification of the natural reservoir of these viruses is one of the most important topics in this field and a fundamental key to understanding their natural history. Despite the discov... | https://pubmed.ncbi.nlm.nih.gov/17712412/ | https://openalex.org/W2054554285 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1612 | true |
PMID_32479636 | Both | 32,479,636 | null | 10.1093/infdis/jiaa290 | Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus | Danielle Porter; Jessica M. Weidner; Laura Gomba; Roy Bannister; Christiana Blair; Robert Jordan; Jay Wells; Kelly S. Wetzel; Nicole L. Garza; Sean Van Tongeren; Ginger Donnelly; Jesse Steffens; Alicia M. Moreau; Jeremy J. Bearss; Eric Lee; Sina Bavari; Tomáš Cihlář; Travis K. Warren | The Journal of Infectious Diseases | 2,020 | Abstract Marburg virus (MARV) is a filovirus with documented human case-fatality rates of up to 90%. Here, we evaluated the therapeutic efficacy of remdesivir (GS-5734) in nonhuman primates experimentally infected with MARV. Beginning 4 or 5 days post inoculation, cynomolgus macaques were treated once daily for 12 days... | https://pubmed.ncbi.nlm.nih.gov/32479636/ | https://openalex.org/W3030369399 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #5622 | true |
PMID_27489944 | OpenAlex | 27,489,944 | null | 10.1371/journal.pntd.0004796 | Transmission or Within-Host Dynamics Driving Pulses of Zoonotic Viruses in Reservoir–Host Populations | Raina K. Plowright; Alison J. Peel; Daniel G. Streicker; Amy T. Gilbert; Hamish McCallum; James L. N. Wood; Michelle L. Baker; Olivier Restif | PLoS neglected tropical diseases | 2,016 | Progress in combatting zoonoses that emerge from wildlife is often constrained by limited knowledge of the biology of pathogens within reservoir hosts. We focus on the host-pathogen dynamics of four emerging viruses associated with bats: Hendra, Nipah, Ebola, and Marburg viruses. Spillover of bat infections to humans a... | https://pubmed.ncbi.nlm.nih.gov/27489944/ | https://openalex.org/W2467600727 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1835 | true |
PMID_19649327 | OpenAlex | 19,649,327 | null | 10.1371/journal.ppat.1000536 | Isolation of Genetically Diverse Marburg Viruses from Egyptian Fruit Bats | Jonathan S. Towner; Brian R. Amman; Tara K. Sealy; Serena A. Carroll; James A. Comer; Alan C. Kemp; Robert Swanepoel; Christopher D. Paddock; Stephen Balinandi; Marina L. Khristova; Pierre Formenty; César G. Albariño; David Miller; Zachary Reed; John Kayiwa; James N. Mills; Deborah Cannon; Patricia W. Greer; Emmanuel B... | PLoS Pathogens | 2,009 | In July and September 2007, miners working in Kitaka Cave, Uganda, were diagnosed with Marburg hemorrhagic fever. The likely source of infection in the cave was Egyptian fruit bats (Rousettus aegyptiacus) based on detection of Marburg virus RNA in 31/611 (5.1%) bats, virus-specific antibody in bat sera, and isolation o... | https://pubmed.ncbi.nlm.nih.gov/19649327/ | https://openalex.org/W2109152434 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #3857 | true |
PMID_26589246 | Both | 26,589,246 | PMC1675587 | 10.1093/ije/dyv307 | Risk factors for transmission of Ebola or Marburg virus disease: a systematic review and meta-analysis | Julii Brainard; Lee Hooper; Katherine Pond; Kelly Edmunds; Paul Hunter | International Journal of Epidemiology | 2,015 | Transmission of filovirus is unlikely except through close contact, especially during the most severe stages of acute illness. More data are needed about the context, intimacy and timing of contact required to raise the odds of disease transmission. Risk factors specific to urban settings may need to be determined. | https://pubmed.ncbi.nlm.nih.gov/26589246/ | https://openalex.org/W2277390423 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #2741 | true |
DOI_38de5479ac43 | OpenAlex | null | null | 10.1101/2023.07.10.23292424 | Marburg Virus Disease outbreaks, mathematical models, and disease parameters: a Systematic Review | Gina Cuomo-Dannenburg; Kelly McCain; Ruth McCabe; H. Juliette T. Unwin; Patrick Doohan; Rebecca K. Nash; Joseph T. Hicks; Kelly Charniga; Cyril Geismar; Ben Lambert; Dariya Nikitin; Janetta Skarp; Jack Wardle; Mara D. Kont; Sangeeta Bhatia; Natsuko Imai; Sabine van Elsland; Anne Cori; Christian Morgenstern; Christian M... | null | 2,023 | Abstract Background Recent Marburg virus disease (MVD) outbreaks in Equatorial Guinea and Tanzania highlighted the importance of better understanding this highly lethal infectious pathogen. Past epidemics of Ebola, COVID-19, and other pathogens have re-emphasised the usefulness of mathematical models in guiding public ... | http://dx.doi.org/10.1101/2023.07.10.23292424 | https://openalex.org/W4384024570 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | null | null | null | false |
PMID_30883555 | OpenAlex | 30,883,555 | null | 10.1371/journal.pntd.0007257 | Marburg virus disease outbreak in Kween District Uganda, 2017: Epidemiological and laboratory findings | Luke Nyakarahuka; Trevor Shoemaker; Stephen Balinandi; Godfrey Chemos; Benon Kwesiga; Sophia Mulei; Jackson Kyondo; Alex Tumusiime; Aaron Kofman; Ben Masiira; Shannon Whitmer; Shelley Brown; Debi Cannon; Cheng‐Feng Chiang; James Graziano; Maria Morales-Betoulle; Ketan Patel; Sara Zufan; Innocent Komakech; Nasan Natseri... | PLoS neglected tropical diseases | 2,019 | This outbreak of MVD occurred as a family cluster with no additional transmission outside of the four related cases. Rapid case detection, prompt laboratory testing at the Uganda National VHF Reference Laboratory and presence of pre-trained, well-prepared national and district rapid response teams facilitated the conta... | https://pubmed.ncbi.nlm.nih.gov/30883555/ | https://openalex.org/W2922424439 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #4747 | true |
PMID_26209681 | Both | 26,209,681 | PMC3437705 | 10.1093/infdis/jiv351 | Multidistrict Outbreak of Marburg Virus Disease—Uganda, 2012 | Barbara Knust; Ilana J. Schafer; Joseph Francis Wamala; Luke Nyakarahuka; Charles Okot; Trevor Shoemaker; Kimberly A. Dodd; Aridth Gibbons; Stephen Balinandi; Alex Tumusiime; Shelley Campbell; Edmund Newman; Estrella Lasry; Hilde Declerck; Yap Boum; Issa Makumbi; Henry Kyobe Bosa; Anthony K. Mbonye; Jane Ruth Aceng; St... | The Journal of Infectious Diseases | 2,015 | In October 2012, a cluster of illnesses and deaths was reported in Uganda and was confirmed to be an outbreak of Marburg virus disease (MVD). Patients meeting the case criteria were interviewed using a standard investigation form, and blood specimens were tested for evidence of acute or recent Marburg virus infection b... | https://pubmed.ncbi.nlm.nih.gov/26209681/ | https://openalex.org/W2268158888 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #3605 | true |
PMID_15078595 | OpenAlex | 15,078,595 | null | 10.3201/eid1001.030125 | Ecologic and Geographic Distribution of Filovirus Disease | A. Townsend Peterson; John Bauer; James N. Mills | Emerging infectious diseases | 2,004 | We used ecologic niche modeling of outbreaks and sporadic cases of filovirus-associated hemorrhagic fever (HF) to provide a large-scale perspective on the geographic and ecologic distributions of Ebola and Marburg viruses. We predicted that filovirus would occur across the Afrotropics: Ebola HF in the humid rain forest... | https://pubmed.ncbi.nlm.nih.gov/15078595/ | https://openalex.org/W2169669039 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #1856 | true |
PMID_36209757 | Both | 36,209,757 | null | 10.1016/s2666-5247(22)00258-0 | Marburg virus outbreak in 2022: a public health concern | Yusha Araf; Sumaiya Tasnim Maliha; Jingbo Zhai; Chunfu Zheng | The Lancet Microbe | 2,022 | Marburg virus—discovered by virologists in Marburg following a 19761WHOMarburg virus disease.https://www.who.int/news-room/fact-sheets/detail/marburg-virus-diseaseDate: August, 2021Date accessed: August 19, 2022Google Scholar outbreak in Marburg and Frankfurt, Germany, and in Belgrade, Serbia2Joi P The next pandemic: M... | https://pubmed.ncbi.nlm.nih.gov/36209757/ | https://openalex.org/W4302759310 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #5294 | true |
PMID_811315 | Both | 811,315 | PMC1675587 | 10.1136/bmj.4.5995.489 | Outbreake of Marburg virus disease in Johannesburg. | J Gear; G A Cassel; A J Gear; B Trappler; Louise Nygaard Clausen; A.M. Meyers; M C Kew; T. H. Bothwell; R Sher; G B Miller; Josef Schneider; H J Koornhof; Gomperts Ed; M Isaäcson; J. H. S. Gear | BMJ | 1,975 | The first recognised outbreak of Marburg virus disease in Africa, and the first since the original epidemic in West Germany and Yugoslavia in 1967, occurred in South Africa in February 1975. The primary case was in a young Australian man , who was admitted to the Johannesburg Hospital after having toured Rhodesia. Two ... | https://pubmed.ncbi.nlm.nih.gov/811315/ | https://openalex.org/W1979049945 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | INCLUDE | INCLUDE | #3795 | true |
PMID_23029039 | Both | 23,029,039 | PMC1626099 | 10.1371/journal.pone.0045479 | Virological and Serological Findings in Rousettus aegyptiacus Experimentally Inoculated with Vero Cells-Adapted Hogan Strain of Marburg Virus | Janusz T. Pawęska; Petrus Jansen van Vuren; Justin Masumu; Patricia A. Leman; Antoinette A. Grobbelaar; Monica Birkhead; Sarah J. Clift; Robert Swanepoel; Alan C. Kemp | PLoS ONE | 2,012 | The Egyptian fruit bat, Rousettus aegyptiacus, is currently regarded as a potential reservoir host for Marburg virus (MARV). However, the modes of transmission, the level of viral replication, tissue tropism and viral shedding pattern remains to be described. Captive-bred R. aegyptiacus, including adult males, females ... | https://pubmed.ncbi.nlm.nih.gov/23029039/ | https://openalex.org/W2039607104 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1868 | true |
PMID_15937495 | Both | 15,937,495 | null | 10.1038/nm1258 | Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses | Steven J.M. Jones; Heinz Feldmann; Ute Ströher; Joan B. Geisbert; Lisa Fernando; Allen Grolla; Hans-Dieter Klenk; Nancy J. Sullivan; Viktor E. Volchkov; Elizabeth A. Fritz; Kathleen M Daddario; Lisa E. Hensley; Peter B. Jahrling; Thomas W. Geisbert | Nature Medicine | 2,005 | Vaccines and therapies are urgently needed to address public health needs stemming from emerging pathogens and biological threat agents such as the filoviruses Ebola virus (EBOV) and Marburg virus (MARV). Here, we developed replication-competent vaccines against EBOV and MARV based on attenuated recombinant vesicular s... | https://pubmed.ncbi.nlm.nih.gov/15937495/ | https://openalex.org/W2030292647 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #2587 | true |
PMID_23202446 | OpenAlex | 23,202,446 | null | 10.3390/v4101878 | Forty-Five Years of Marburg Virus Research | Kristina Brauburger; Adam J. Hume; Elke Mühlberger; Judith Olejnik | Viruses | 2,012 | In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg virus, is one of the most deadly human pathogens. This article provides a comprehensive overview of our current knowledge about Marburg ... | https://pubmed.ncbi.nlm.nih.gov/23202446/ | https://openalex.org/W2133984373 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #2735 | true |
PMID_9988154 | Both | 9,988,154 | null | 10.1086/514322 | An Introduction to Ebola: The Virus and the Disease | CJ Peters; James W. LeDuc | The Journal of Infectious Diseases | 1,999 | A number of colleagues, both in the laboratory and in the field, agreed to prepare reports reflecting recent research, thus permitting this supplement to the Journal of Infectious Dis- Ebola, the Second Known Filovirus eases, which provides a single source for substantial new, peerreviewed information. We have somewhat... | https://pubmed.ncbi.nlm.nih.gov/9988154/ | https://openalex.org/W1991345768 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1857 | true |
PMID_12089242 | Both | 12,089,242 | PMC1586880 | 10.1128/jcm.40.7.2323-2330.2002 | Rapid Detection and Quantification of RNA of Ebola and Marburg Viruses, Lassa Virus, Crimean-Congo Hemorrhagic Fever Virus, Rift Valley Fever Virus, Dengue Virus, and Yellow Fever Virus by Real-Time Reverse Transcription-PCR | Christian Drosten; Stephan Göttig; Stefan Schilling; Marcel Asper; Marcus Panning; Herbert Schmitz; Stephan Günther | Journal of Clinical Microbiology | 2,002 | ABSTRACT Viral hemorrhagic fevers (VHFs) are acute infections with high case fatality rates. Important VHF agents are Ebola and Marburg viruses (MBGV/EBOV), Lassa virus (LASV), Crimean-Congo hemorrhagic fever virus (CCHFV), Rift Valley fever virus (RVFV), dengue virus (DENV), and yellow fever virus (YFV). VHFs are clin... | https://pubmed.ncbi.nlm.nih.gov/12089242/ | https://openalex.org/W2107922358 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #2511 | true |
PMID_17370518 | OpenAlex | 17,370,518 | null | 10.3201/eid1301.060837 | Panmicrobial Oligonucleotide Array for Diagnosis of Infectious Diseases | Gustavo Palacios; Phenix‐Lan Quan; Omar Jabado; Sean Conlan; David L. Hirschberg; Yang Liu; Junhui Zhai; Neil Renwick; Jeffrey Hui; Hédi Hegyi; Allen Grolla; James E. Strong; Jonathan S. Towner; Thomas W. Geisbert; Peter B. Jahrling; C. Büchen‐Osmond; Heinz Ellerbrok; María Paz Sánchez‐Seco; Yves A. Lussier; Pierre For... | Emerging infectious diseases | 2,007 | To facilitate rapid, unbiased, differential diagnosis of infectious diseases, we designed GreeneChipPm, a panmicrobial microarray comprising 29,455 sixty-mer oligonucleotide probes for vertebrate viruses, bacteria, fungi, and parasites. Methods for nucleic acid preparation, random primed PCR amplification, and labeling... | https://pubmed.ncbi.nlm.nih.gov/17370518/ | https://openalex.org/W2100095805 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1907 | true |
DOI_1f7dbb45fe67 | OpenAlex | null | null | 10.1093/trstmh/trv024 | Mapping the zoonotic niche of Marburg virus disease in Africa | David M. Pigott; Nick Golding; Adrian Mylne; Zhi Huang; Daniel J. Weiss; Oliver J. Brady; Moritz U. G. Kraemer; Simon I Hay | Transactions of the Royal Society of Tropical Medicine and Hygiene | 2,015 | Background: Marburg virus disease (MVD) describes a viral haemorrhagic fever responsible for a number of out-breaks across eastern and southern Africa. It is a zoonotic disease, with the Egyptian rousette (Rousettus aegyp-tiacus) identified as a reservoir host. Infection is suspected to result from contact between this... | https://doi.org/10.1093/trstmh/trv024 | https://openalex.org/W2197717400 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #1849 | true |
PMID_16775337 | Both | 16,775,337 | PMC237485 | 10.1128/jvi.00069-06 | Marburgvirus Genomics and Association with a Large Hemorrhagic Fever Outbreak in Angola | Jonathan S. Towner; Marina L. Khristova; Tara K. Sealy; Martin J. Vincent; Bobbie R. Erickson; Darcy A. Bawiec; Amy L. Hartman; James A. Comer; Sherif R. Zaki; Ute Ströher; Filomena Gomes da Silva; Fernando del Castillo; Pierre E. Rollin; Thomas G. Ksiazek; Stuart T. Nichol | Journal of Virology | 2,006 | ABSTRACT In March 2005, the Centers for Disease Control and Prevention (CDC) investigated a large hemorrhagic fever (HF) outbreak in Uige Province in northern Angola, West Africa. In total, 15 initial specimens were sent to CDC, Atlanta, Ga., for testing for viruses associated with viral HFs known to be present in West... | https://pubmed.ncbi.nlm.nih.gov/16775337/ | https://openalex.org/W1993413375 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | INCLUDE | INCLUDE | #1613 | true |
PMID_18216185 | Both | 18,216,185 | PMC224991 | 10.1128/cvi.00431-07 | Vaccine To Confer to Nonhuman Primates Complete Protection against Multistrain Ebola and Marburg Virus Infections | Dana L. Swenson; Danher Wang; Min Luo; Kelly L. Warfield; Jan Woraratanadharm; David H. Holman; John Y. Dong; William D. Pratt | Clinical and Vaccine Immunology | 2,008 | ABSTRACT Filoviruses (Ebola and Marburg viruses) are among the deadliest viruses known to mankind, with mortality rates nearing 90%. These pathogens are highly infectious through contact with infected body fluids and can be easily aerosolized. Additionally, there are currently no licensed vaccines available to prevent ... | https://pubmed.ncbi.nlm.nih.gov/18216185/ | https://openalex.org/W2138000140 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #1646 | true |
PMID_30053050 | OpenAlex | 30,053,050 | null | 10.1093/infdis/jiy367 | New Insights Into Marburg Virus Disease Pathogenesis in the Rhesus Macaque Model | Timothy K. Cooper; Jennifer Sword; Joshua C. Johnson; Amanda Bonilla; Randy Hart; David X. Liu; John G. Bernbaum; Kurt Cooper; Peter B. Jahrling; Lisa E. Hensley | The Journal of Infectious Diseases | 2,018 | Previously, several studies have been performed to delineate the development and progression of Marburg virus infection in nonhuman primates (NHPs), primarily to clarify the mechanisms of severe (fatal) disease. After the 2013-2016 Ebola virus disease (EVD) epidemic in Western Africa, there has been a reassessment of t... | https://pubmed.ncbi.nlm.nih.gov/30053050/ | https://openalex.org/W2883602978 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #2572 | true |
PMID_18258034 | OpenAlex | 18,258,034 | null | 10.3201/eid1312.071115 | Studies of Reservoir Hosts for Marburg Virus | Robert Swanepoel; Sheilagh Smit; Pierre E. Rollin; Pierre Formenty; Patricia A. Leman; Alan C. Kemp; Felicity J. Burt; Antoinette A. Grobbelaar; Janice E. Croft; Daniel G. Bausch; H. Zeller; Herwig Leirs; Leo Braack; Modeste L. Libande; Sherif R. Zaki; Stuart T. Nichol; Thomas G. Ksiazek; Janusz T. Pawęska; on behalf o... | Emerging infectious diseases | 2,007 | To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivo... | https://pubmed.ncbi.nlm.nih.gov/18258034/ | https://openalex.org/W2061033820 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #1648 | true |
PMID_15588056 | Both | 15,588,056 | null | 10.1089/bsp.2004.2.186 | Marburg and Ebola Viruses as Aerosol Threats | Elizabeth K. Leffel; Douglas S. Reed | Biosecurity and Bioterrorism Biodefense Strategy Practice and Science | 2,004 | Ebola and Marburg viruses are the sole members of the genus Filovirus in the family Filoviridae. There has been considerable media attention and fear generated by outbreaks of filoviruses because they can cause a severe viral hemorrhagic fever (VHF) syndrome that has a rapid onset and high mortality. Although they are ... | https://pubmed.ncbi.nlm.nih.gov/15588056/ | https://openalex.org/W1997380883 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | INCLUDE | #2171 | true |
PMID_25297522 | Both | 25,297,522 | null | 10.1002/path.4456 | Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses | Roosecelis B. Martines; Dianna Ng; Patricia W. Greer; Pierre E. Rollin; Sherif R. Zaki | The Journal of Pathology | 2,014 | Abstract Ebola viruses and Marburg viruses include some of the most virulent and fatal pathogens known to humans. These viruses cause severe haemorrhagic fevers, with case fatality rates in the range 25–90%. The diagnosis of filovirus using formalin‐fixed tissues from fatal cases poses a significant challenge. The most... | https://pubmed.ncbi.nlm.nih.gov/25297522/ | https://openalex.org/W1545010974 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #2062 | true |
PMID_12853377 | OpenAlex | 12,853,377 | null | 10.1128/cdli.10.4.506-513.2003 | Immunological Methods for Detection and Identification of Infectious Disease and Biological Warfare Agents | Anne Harwood Peruski; Leonard F. Peruski | Clinical and Vaccine Immunology | 2,003 | PROBLEMBW agents.The release of a biological weapon (BW) agent by a terrorist group or military force would likely be silent and undetectable or nearly so.As shown by anthrax attack during the fall of 2001 in the eastern United States, patients would begin appearing at hospitals and clinics within several days of expos... | https://pubmed.ncbi.nlm.nih.gov/12853377/ | https://openalex.org/W2163553667 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | null | null | null | false |
PMID_29982632 | Both | 29,982,632 | PMC1277264 | 10.1093/infdis/jiy332 | The Calcium Channel Blocker Bepridil Demonstrates Efficacy in the Murine Model of Marburg Virus Disease | Lisa Evans DeWald; Julie Dyall; Jennifer Sword; Lisa Torzewski; Huanying Zhou; Elena Postnikova; Erin Kollins; Isis Alexander; Robin Gross; Yu Cong; Dawn M. Gerhardt; Reed F. Johnson; Gene G. Olinger; Michael R. Holbrook; Lisa E. Hensley; Peter B. Jahrling | The Journal of Infectious Diseases | 2,018 | No therapeutics are approved for the treatment of filovirus infections. Bepridil, a calcium channel blocker developed for treating angina, was identified as a potent inhibitor of filoviruses in vitro, including Ebola and Marburg viruses, and Ebola virus in vivo. We evaluated the efficacy of bepridil in a lethal mouse m... | https://pubmed.ncbi.nlm.nih.gov/29982632/ | https://openalex.org/W2901226061 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #2537 | true |
PMID_36051815 | OpenAlex | 36,051,815 | null | 10.1016/j.amsu.2022.104377 | Marburg virus outbreak in Ghana: An impending crisis | Jack Wellington; Ayça Nur; Nicholas Aderinto; Olivier Uwishema; Hassan Chaito; Olutola Awosiku; Yusuf Jaafer Al Tarawneh; Jana Abdul Nasser Sharafeddine; Chinyere Vivian Patrick Onyeaka; Helen Onyeaka | Annals of Medicine and Surgery | 2,022 | Since the initial identification of the Marburg virus in 1967, it has sporadically emerged in several countries throughout Africa, including Zimbabwe, Kenya, South Africa, the Democratic Republic of the Congo (DRC), Uganda, and Zimbabwe. Due to the concurrent occurrence of other epidemics like the coronavirus disease 2... | https://pubmed.ncbi.nlm.nih.gov/36051815/ | https://openalex.org/W4292260941 | null | marburg | Marburg virus AND ((transmission OR transmissibility OR transmissible OR transmitted OR transmitting OR transmit OR epidemiology OR epidemiological OR epidemiologic) OR (model OR models OR modeling OR modelling OR modeled OR modelled NOT (image OR images OR imaging)) OR (severity OR "case fatality ratio" OR "case fatal... | 2026-01-26T01:38:28+00:00 | null | null | null | null | null | EXCLUDE | EXCLUDE | #4738 | true |
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AgentSLR: Priority Pathogens Dataset
Paper
Codebase
Project Website
This dataset accompanies the paper AgentSLR: Automating Systematic Literature Reviews in Epidemiology with Agentic AI. It brings together large-scale research articles that undergo the scientific rigours required to create systematic literature reviews. We present the metadata of articles, human abstract and article screening labels, and structured human data extractions for epidemiological parameters, transmission models, and outbreaks across WHO-designated priority pathogens.
Human labels in this release come from real-world reviews conducted by the Pathogen Epidemiology Review Group (PERG) at Imperial College London. These labels reflect expert review decisions rather than synthetic annotation, and they ground the evaluation of AgentSLR in operational epidemiological review workflows.
Figure: Data flow through a systematic literature review: a large corpus of harvested articles is progressively filtered through abstract and full-text screening to yield a relevant subset, which then undergoes structured data extraction across three output types (parameters, transmission models and outbreaks) that feed into living review generation.
The release covers nine priority pathogens:
- Marburg virus
- Ebola virus
- Lassa fever
- SARS-CoV-1
- Zika virus
- MERS-CoV
- Nipah virus
- Rift Valley fever virus
- CCHF virus
This release includes 218,325 harvested article records, 37,155 PERG-linked human screening records across seven pathogens, 3,808 human parameter extractions, 687 human transmission-model extractions and 189 human outbreak extractions.
Harvest metadata was generated on 26 January 2026 (UTC). The full AgentSLR toolkit, covering harvesting, PDF retrieval, OCR/PDF-to-Markdown conversion, screening, full-text processing, extraction and report generation, is available on GitHub.
This release contains broad harvesting metadata, but downloadable full text is narrower: roughly 40% of records in the January 2026 harvest yielded a downloadable PDF, with variation driven by open-access status, publisher availability, hosting platform and retrieval route (including proxy and institutional access).
PERG (Humans) and AgentSLR Pathogen Coverage
The table below mirrors the review-overlap summary from the paper.
| Pathogen | PERG* | AgentSLR | Matched |
|---|---|---|---|
| ● Marburg virus | 2,593 | 6,501 | 762 (29.4%) |
| ● Ebola virus | 11,605 | 23,226 | 3,938 (33.9%) |
| ● Lassa fever | 2,131 | 6,514 | 647 (30.4%) |
| ● SARS-CoV-1 | 12,280 | 7,540 | 1,967 (16.0%) |
| ● Zika virus | 10,510 | 3,103 | 2,128 (20.2%) |
| ● MERS-CoV | 19,656 | 23,204 | 5,675 (28.9%) |
| ● Nipah virus | 1,458 | 5,103 | 664 (45.5%) |
| ● Rift Valley fever virus | - | 6,810 | - |
| ● CCHF virus | - | 3,478 | - |
| Total† | 60,233 | 75,191 | 15,781 (26.2%) |
● Published PERG review ● In data extraction by PERG ● Screening not yet conducted by PERG
* Articles post deduplication and empty abstract removal.† Excludes Rift Valley fever virus and CCHF article counts, matching the paper table.
Dataset Organisation
The dataset is organised into four config types:
- Harvest Metadata and Screening: one config with nine pathogen splits
- Parameter Extraction - {Pathogen}: one config per pathogen
- Transmission Model Extraction - {Pathogen}: one config per pathogen
- Outbreak Extraction - {Pathogen}: one config per pathogen
The harvest config contains PERG screening labels for all nine pathogens. For RVF and CCHF, screening columns are present but null as PERG labels were not available for this release. Human screening labels are only populated where perg_subset == True. The covidence_id key links screened articles in the harvest table to their corresponding human extraction records.
As data extraction schemas vary by pathogen, each pathogen for which human data extraction has been concluded is published as an individual config on the Hub, covering Ebola, Lassa, SARS and Zika for parameters and transmission models, and Lassa and Zika for outbreaks.
Using datasets:
from datasets import load_dataset
repo_id = "OxRML/AgentSLR"
marburg_harvest = load_dataset(repo_id, "Harvest Metadata and Screening", split="marburg")
ebola_parameters = load_dataset(repo_id, "Parameter Extraction - Ebola", split="ebola")
zika_models = load_dataset(repo_id, "Transmission Model Extraction - Zika")
lassa_outbreaks = load_dataset(repo_id, "Outbreak Extraction - Lassa")
Access, Copyright and Licensing
This repository distributes structured review data, bibliographic metadata, identifiers, URLs and abstracts where present in source records. It does not redistribute publisher PDFs.
The legal status of underlying sources is not uniform. OpenAlex releases its data under CC0 (FAQ) and notes that original copyright remains with the source for PDFs (full-text PDF docs). PubMed provides citations and abstracts rather than full-text articles (About PubMed), and NLM does not claim copyright on PubMed abstracts, though publishers or authors may retain rights in the underlying materials (NCBI Policies, PubMed Disclaimer).
This release provides metadata and structured outputs only. Downstream redistribution of article text or PDFs should follow source-specific rights and licences. To run the full AgentSLR pipeline, use the main codebase for PDF retrieval, OCR/PDF-to-Markdown conversion, full-text screening and structured data extraction.
NOTE: This summary is provided for transparency and reproducibility and should not be treated as legal advice.
Citation
If you use the paper, dataset or codebase, please cite our paper:
@misc{padarha2026agentslr,
title={AgentSLR: Automating Systematic Literature Reviews in Epidemiology with Agentic AI},
author={Shreyansh Padarha and Ryan Othniel Kearns and Tristan Naidoo and Lingyi Yang and Łukasz Borchmann and Piotr BŁaszczyk and Christian Morgenstern and Ruth McCabe and Sangeeta Bhatia and Philip H. Torr and Jakob Foerster and Scott A. Hale and Thomas Rawson and Anne Cori and Elizaveta Semenova and Adam Mahdi},
year={2026},
eprint={2603.22327},
archivePrefix={arXiv},
primaryClass={cs.IR},
url={https://arxiv.org/abs/2603.22327},
}
When citing our work, please also cite the epireview R package, which underpins the PERG manual review workflows and structured data schemas this dataset builds on:
@Manual{epireview2025,
title = {epireview: Tools to update and summarise the latest pathogen data from the Pathogen Epidemiology Review Group (PERG)},
author = {Tristan Naidoo and Rebecca Nash and Christian Morgenstern and Patrick Doohan and Ruth McCabe and Joshua Lambert and Richard Sheppard and Cosmo Santoni and Thomas Rawson and Shazia Ruybal-Pes{\'a}ntez and Juliette H Unwin and Gina Cuomo-Dannenburg and Kelly McCain and Joseph Hicks and Anne Cori and Sangeeta Bhatia},
year = {2025},
note = {R package version 1.4.4},
url = {https://github.com/mrc-ide/epireview}
}
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Size of downloaded dataset files:
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Number of rows:
223,009